孕期头痛管理的神经调节疗法
Neuromodulation for Headache Management in Pregnancy.
作者信息
Smirnoff Liza, Bravo Michelle, Hyppolite Tayina
机构信息
Department of Neurology - Headache Division, University of Miami Health, University of Miami School of Medicine, 1120 NW 14th Street, 13th Floor, Miami, FL, 33136, USA.
出版信息
Curr Pain Headache Rep. 2025 Jan 7;29(1):14. doi: 10.1007/s11916-024-01344-1.
PURPOSE OF REVIEW
Management of primary headache disorders during pregnancy is limited due to known teratogenicity or unknown safety of many currently available pharmaceutical therapies. Here, we explore the safety and efficacy of non-invasive neuromodulatory devices as another treatment modality for pregnant patients.
RECENT FINDINGS
There are six FDA-cleared, non-invasive neuromodulatory devices currently available for the management of headache that include remote electrical neuromodulation (REN), noninvasive vagal nerve stimulation (nVNS), external trigeminal nerve stimulation (eTNS), single-pulse transcranial magnetic stimulation (sTMS), and external concurrent occipital and trigeminal neurostimulation (eCOT-NS). Neuromodulatory devices are a safe, effective, and well tolerated non-pharmacological option for migraine and other primary headache disorders. Although evidence of safety and tolerability use in pregnancy is limited, they may serve as a therapeutic alternative or adjunct to improve the care of our pregnant patients.
综述目的
由于许多现有药物疗法已知的致畸性或未知的安全性，孕期原发性头痛疾病的管理受到限制。在此，我们探讨非侵入性神经调节设备作为孕妇另一种治疗方式的安全性和有效性。
最新发现
目前有六种获得美国食品药品监督管理局（FDA）批准的非侵入性神经调节设备可用于治疗头痛，包括远程电神经调节（REN）、非侵入性迷走神经刺激（nVNS）、外部三叉神经刺激（eTNS）、单脉冲经颅磁刺激（sTMS）以及外部枕神经和三叉神经同时刺激（eCOT-NS）。神经调节设备是治疗偏头痛和其他原发性头痛疾病的一种安全、有效且耐受性良好的非药物选择。尽管孕期使用的安全性和耐受性证据有限，但它们可作为一种治疗选择或辅助手段，以改善对孕妇的护理。
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