Department of Conservative Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Eur Endod J. 2023 Mar;8(2):105-113. doi: 10.14744/eej.2022.83097.
To answer the question: 'Does the pharmacological management of dental anxiety influence pain occurrence during root canal treatment?'
Searches on MEDLINE/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE and Open Grey were conducted until September 02, 2022. Only randomised clinical trials were included. The Cochrane risk of bias tool for randomized trials (RoB 2) was used. The overall quality of evidence was assessed through the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tool.
Initial screening resulted in 811 studies. Three hundred seventy-three were excluded for being duplicates. Of 438 eligible papers, ten studies met the inclusion criteria and were selected for full-text reading. Four studies were included in the final analysis. Three studies had a low risk of bias, and one was a high risk. GRADE demonstrated a low quality of evidence.
There is insufficient evidence to determine whether the pharmacological control of anxiety can influence intraoperative pain occurrence. (EEJ-2022-08-096).
回答以下问题：“牙科焦虑症的药理学管理是否会影响根管治疗过程中的疼痛发生？”
截至 2022 年 9 月 2 日，在 MEDLINE/PubMed、Cochrane 图书馆、Web of Science、Scopus、EMBASE 和 Open Grey 上进行了检索。仅纳入随机临床试验。使用 Cochrane 随机试验偏倚风险工具（RoB 2）评估偏倚风险。通过推荐评估、制定与评价（GRADE）工具评估证据的总体质量。
最初筛选出 811 项研究。373 项因重复而被排除。在 438 篇合格的论文中，有 10 项研究符合纳入标准并进行了全文阅读。最终分析纳入了 4 项研究。其中 3 项研究的偏倚风险较低，1 项研究的偏倚风险较高。GRADE 表明证据质量低。
目前尚无足够的证据确定焦虑症的药物控制是否会影响术中疼痛的发生。（EEJ-2022-08-096）。
