Matson P L, Tuvik A I, O'Halloran F, Yovich J L
J In Vitro Fert Embryo Transf. 1986 Apr;3(2):110-3. doi: 10.1007/BF01139356.
The relevance of the postcoital test (PCT) in relation to the fertilization rate of oocytes was determined in an analysis of 66 couples in an in vitro fertilization (IVF) program. The test is routinely performed in the workup of all IVF patients and is accurately timed to the immediate preovulatory period by daily hormonal, cervical mucus, and ultrasound monitoring. Cases demonstrating antispermatozoal antibodies in the serum of either partner, in cervical mucus, or in semen were excluded. There was no significant difference in the fertilization rate of oocytes whether the PCT result was negative, equivocal, or positive, and the finding was the same in both normospermic and oligospermic groups. It is concluded that the PCT is of no value in predicting the outcome of IVF and, conversely, IVF should be considered as a therapeutic option for couples with a negative PCT.
通过对体外受精(IVF)项目中的66对夫妇进行分析,确定了性交后试验(PCT)与卵母细胞受精率之间的相关性。该试验在所有IVF患者的检查过程中常规进行,并通过每日激素、宫颈黏液和超声监测准确地安排在排卵前期。排除任何一方血清、宫颈黏液或精液中显示抗精子抗体的病例。无论PCT结果为阴性、不明确或阳性,卵母细胞的受精率均无显著差异,正常精子症组和少精子症组的结果相同。结论是,PCT对预测IVF结果没有价值,相反,IVF应被视为PCT结果为阴性的夫妇的一种治疗选择。