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性交后试验在预测人类卵母细胞受精方面的价值。

The value of the postcoital test in predicting the fertilization of human oocytes.

作者信息

Matson P L, Tuvik A I, O'Halloran F, Yovich J L

出版信息

J In Vitro Fert Embryo Transf. 1986 Apr;3(2):110-3. doi: 10.1007/BF01139356.

DOI:10.1007/BF01139356
PMID:3701180
Abstract

The relevance of the postcoital test (PCT) in relation to the fertilization rate of oocytes was determined in an analysis of 66 couples in an in vitro fertilization (IVF) program. The test is routinely performed in the workup of all IVF patients and is accurately timed to the immediate preovulatory period by daily hormonal, cervical mucus, and ultrasound monitoring. Cases demonstrating antispermatozoal antibodies in the serum of either partner, in cervical mucus, or in semen were excluded. There was no significant difference in the fertilization rate of oocytes whether the PCT result was negative, equivocal, or positive, and the finding was the same in both normospermic and oligospermic groups. It is concluded that the PCT is of no value in predicting the outcome of IVF and, conversely, IVF should be considered as a therapeutic option for couples with a negative PCT.

摘要

通过对体外受精(IVF)项目中的66对夫妇进行分析,确定了性交后试验(PCT)与卵母细胞受精率之间的相关性。该试验在所有IVF患者的检查过程中常规进行,并通过每日激素、宫颈黏液和超声监测准确地安排在排卵前期。排除任何一方血清、宫颈黏液或精液中显示抗精子抗体的病例。无论PCT结果为阴性、不明确或阳性,卵母细胞的受精率均无显著差异,正常精子症组和少精子症组的结果相同。结论是,PCT对预测IVF结果没有价值,相反,IVF应被视为PCT结果为阴性的夫妇的一种治疗选择。

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1
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本文引用的文献

1
The limitations of in vitro fertilization from males with severe oligospermia and abnormal sperm morphology.严重少精子症和精子形态异常男性体外受精的局限性。
J In Vitro Fert Embryo Transf. 1984 Sep;1(3):172-9. doi: 10.1007/BF01139210.
2
In-vitro fertilization in Western Australia. A viable service programme.西澳大利亚的体外受精。一项可行的服务项目。
Med J Aust. 1984 May 26;140(11):645-9.
3
Application of in-vitro fertilisation in cases of a poor post-coital test.性交后试验结果不佳情况下体外受精的应用。
Lancet. 1984 Sep 8;2(8402):583. doi: 10.1016/s0140-6736(84)90807-9.
4
Human in-vitro fertilisation, in-vivo sperm penetration of cervical mucus, and unexplained infertility.
Lancet. 1984 Aug 4;2(8397):245-6. doi: 10.1016/s0140-6736(84)90296-4.
5
The postcoital test: what is normal?性交后试验:何为正常?
Br Med J. 1978 Apr 1;1(6116):818. doi: 10.1136/bmj.1.6116.818.
6
Immunity to spermatozoa.
Clin Obstet Gynaecol. 1979 Dec;6(3):385-402.