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Mpox virus infects and injures human kidney organoids, but responding to antiviral treatment.

作者信息

Li Pengfei, Du Zhaoyu, Lamers Mart M, Incitti Roberto, Tejeda-Mora Hector, Li Shengbing, Schraauwen Rick, van den Bosch Thierry P P, de Vries Annemarie C, Alam Intikhab S, Haagmans Bart L, Hoogduijn Martin J, Pan Qiuwei

机构信息

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

Erasmus MC Transplant Institute, Department of Internal Medicine, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

出版信息

Cell Discov. 2023 Apr 3;9(1):34. doi: 10.1038/s41421-023-00545-z.

DOI:10.1038/s41421-023-00545-z
PMID:37012235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10070611/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d55/10070611/ce7555b04665/41421_2023_545_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d55/10070611/ce7555b04665/41421_2023_545_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d55/10070611/ce7555b04665/41421_2023_545_Fig1_HTML.jpg

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Nat Commun. 2022 Oct 8;13(1):5943. doi: 10.1038/s41467-022-33623-z.
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Viral loads in clinical samples of men with monkeypox virus infection: a French case series.猴痘病毒感染男性临床样本中的病毒载量:一项法国病例系列研究。
Lancet Infect Dis. 2023 Jan;23(1):74-80. doi: 10.1016/S1473-3099(22)00586-2. Epub 2022 Sep 29.
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Transmission characteristics, replication patterns and clinical manifestations of human monkeypox virus-an in-depth analysis of four cases from Germany.
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Emerg Microbes Infect. 2025 Dec;14(1):2477639. doi: 10.1080/22221751.2025.2477639. Epub 2025 Mar 18.
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Clinical applications of human organoids.人类类器官的临床应用。
Nat Med. 2025 Feb;31(2):409-421. doi: 10.1038/s41591-024-03489-3. Epub 2025 Feb 3.
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