Gibson Jordan, McGrath Kaitlin, Miller Robert J H, Sumner Glen, Clarke Brian
Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada.
CJC Open. 2022 Dec 26;5(3):237-249. doi: 10.1016/j.cjco.2022.12.008. eCollection 2023 Mar.
Pulmonary artery pressure (PAP) monitoring reduces heart failure (HF) hospitalizations (HFHs) and improves quality of life in New York Heart Association (NYHA) class III HF. We evaluated the impact of PAP monitoring on outcomes and health spending in a Canadian ambulatory HF cohort.
Twenty NYHA III HF patients underwent wireless PAP implantation at Foothills Medical Centre, Calgary, Alberta. Baseline, and 3-, 6-, 9-, and 12-month assessments of laboratory parameters, hemodynamics, 6-minute walk text and Kansas City Cardiomyopathy Questionnaire scores were collected. Healthcare costs 1 year pre- and post-implantation were collected from administrative databases.
Mean age was 70.6 years; 45% were female. Results were as follows: an 88% reduction in emergency room visits ( = 0.0009); an 87% reduction in HFHs ( < 0.0003); a 29% reduction in heart function clinic visits ( = 0.033), and a 178% increase in nurse calls ( < 0.0002). Questionnaire and 6-minute walk test scores at baseline vs last follow-up were 45.4 vs 48.4 ( = 0.48) and 364.4 vs 402.8 m ( = 0.58), respectively. Mean PAP at baseline vs follow-up was 31.5 vs 24.8 mm Hg ( = 0.005). NYHA class improved by at least one class in 85% of patients. Mean measurable HF-related spending preimplantation was CAD$29,814 per patient per year and postimplantation was CAD$25,642 per patient per year (including device cost).
PAP monitoring demonstrated reductions in HFHs, and emergency room and heart function clinic visits, with improvements in NYHA class. Although further economic evaluation is needed, these results support the use of PAP monitoring as an effective and cost-neutral tool in HF management in appropriately selected patients in a publicly funded healthcare system.
肺动脉压(PAP)监测可减少心力衰竭(HF)住院次数(HFHs),并改善纽约心脏协会(NYHA)III级HF患者的生活质量。我们评估了PAP监测对加拿大门诊HF队列患者的预后和医疗支出的影响。
20例NYHA III级HF患者在艾伯塔省卡尔加里市山麓医疗中心接受了无线PAP植入术。收集患者的实验室参数、血流动力学、6分钟步行试验和堪萨斯城心肌病问卷评分的基线数据,以及术后3、6、9和12个月的评估数据。从行政数据库中收集植入术前1年和术后1年的医疗费用。
平均年龄为70.6岁;45%为女性。结果如下:急诊就诊次数减少88%(P = 0.0009);HFHs减少87%(P < 0.0003);心脏功能门诊就诊次数减少29%(P = 0.033),护士呼叫次数增加178%(P < 0.0002)。基线时与末次随访时的问卷评分和6分钟步行试验评分分别为45.4对48.4(P = 0.48)和364.4对402.8米(P = 0.58)。基线时与随访时的平均PAP分别为31.5对24.8 mmHg(P = 0.005)。85%的患者NYHA分级至少改善了一级。植入术前与术后每位患者每年与HF相关的可测量平均支出分别为29,814加元和25,642加元(包括设备成本)。
PAP监测显示HFHs、急诊就诊次数和心脏功能门诊就诊次数减少,NYHA分级改善。尽管需要进一步的经济评估,但这些结果支持在公共资助的医疗系统中,将PAP监测作为一种有效且成本中性的工具,用于适当选择的HF患者的管理。