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The State of Heart Failure Care in Canada: Minimal Improvement in Readmissions Over Time Despite an Increased Number of Evidence-Based Therapies.加拿大心力衰竭护理状况:尽管循证疗法数量增加,但再入院率长期以来改善甚微。
CJC Open. 2022 Aug 12;4(8):667-675. doi: 10.1016/j.cjco.2022.04.011. eCollection 2022 Aug.
2
Real-world evidence in a national health service: results of the UK CardioMEMS HF System Post-Market Study.真实世界证据在国民保健服务中的应用:英国 CardioMEMS HF 系统上市后研究结果。
ESC Heart Fail. 2022 Feb;9(1):48-56. doi: 10.1002/ehf2.13748. Epub 2021 Dec 9.
3
Trends in Heart Failure Hospitalizations in the US from 2008 to 2018.2008 年至 2018 年美国心力衰竭住院治疗趋势。
J Card Fail. 2022 Feb;28(2):171-180. doi: 10.1016/j.cardfail.2021.08.020. Epub 2021 Sep 15.
4
Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial.基于血流动力学的心力衰竭管理(GUIDE-HF):一项随机对照试验。
Lancet. 2021 Sep 11;398(10304):991-1001. doi: 10.1016/S0140-6736(21)01754-2. Epub 2021 Aug 27.
5
Remote Hemodynamic Monitoring Equally Reduces Heart Failure Hospitalizations in Women and Men in Clinical Practice: A Sex-Specific Analysis of the CardioMEMS Post-Approval Study.临床实践中远程血液动力学监测同样减少女性和男性心力衰竭住院:CardioMEMS 上市后研究的性别特异性分析。
Circ Heart Fail. 2021 Jun;14(6):e007892. doi: 10.1161/CIRCHEARTFAILURE.120.007892. Epub 2021 Jun 15.
6
Lower Rates of Heart Failure and All-Cause Hospitalizations During Pulmonary Artery Pressure-Guided Therapy for Ambulatory Heart Failure: One-Year Outcomes From the CardioMEMS Post-Approval Study.肺动脉压指导治疗门诊心力衰竭:心脏 MEMES 上市后研究的一年结果与心力衰竭和全因住院率降低有关。
Circ Heart Fail. 2020 Aug;13(8):e006863. doi: 10.1161/CIRCHEARTFAILURE.119.006863. Epub 2020 Aug 6.
7
Pulmonary artery pressure-guided therapy in ambulatory patients with symptomatic heart failure: the CardioMEMS European Monitoring Study for Heart Failure (MEMS-HF).有症状心力衰竭门诊患者的肺动脉压力引导治疗:欧洲心力衰竭心脏MEMS监测研究(MEMS-HF)
Eur J Heart Fail. 2020 Oct;22(10):1891-1901. doi: 10.1002/ejhf.1943. Epub 2020 Aug 9.
8
Implantable devices for heart failure monitoring: the CardioMEMS™ system.用于心力衰竭监测的可植入设备:CardioMEMS™ 系统。
Eur Heart J Suppl. 2019 Dec;21(Suppl M):M50-M53. doi: 10.1093/eurheartj/suz265. Epub 2019 Dec 31.
9
A Systems-Based Analysis of the CardioMEMS HF Sensor for Chronic Heart Failure Management.用于慢性心力衰竭管理的CardioMEMS HF传感器的基于系统的分析。
Cardiol Res Pract. 2019 Jul 17;2019:7979830. doi: 10.1155/2019/7979830. eCollection 2019.
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An update on the CardioMEMS pulmonary artery pressure sensor.CardioMEMS肺动脉压力传感器的最新情况。
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动态肺动脉压监测可降低症状性心力衰竭的成本并改善预后:一项加拿大单中心经验。

Ambulatory Pulmonary Artery Pressure Monitoring Reduces Costs and Improves Outcomes in Symptomatic Heart Failure: A Single-Centre Canadian Experience.

作者信息

Gibson Jordan, McGrath Kaitlin, Miller Robert J H, Sumner Glen, Clarke Brian

机构信息

Libin Cardiovascular Institute and Department of Cardiac Sciences, Foothills Medical Centre, University of Calgary, Calgary Alberta, Canada.

出版信息

CJC Open. 2022 Dec 26;5(3):237-249. doi: 10.1016/j.cjco.2022.12.008. eCollection 2023 Mar.

DOI:10.1016/j.cjco.2022.12.008
PMID:37013072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10066443/
Abstract

BACKGROUND

Pulmonary artery pressure (PAP) monitoring reduces heart failure (HF) hospitalizations (HFHs) and improves quality of life in New York Heart Association (NYHA) class III HF. We evaluated the impact of PAP monitoring on outcomes and health spending in a Canadian ambulatory HF cohort.

METHODS

Twenty NYHA III HF patients underwent wireless PAP implantation at Foothills Medical Centre, Calgary, Alberta. Baseline, and 3-, 6-, 9-, and 12-month assessments of laboratory parameters, hemodynamics, 6-minute walk text and Kansas City Cardiomyopathy Questionnaire scores were collected. Healthcare costs 1 year pre- and post-implantation were collected from administrative databases.

RESULTS

Mean age was 70.6 years; 45% were female. Results were as follows: an 88% reduction in emergency room visits ( = 0.0009); an 87% reduction in HFHs ( < 0.0003); a 29% reduction in heart function clinic visits ( = 0.033), and a 178% increase in nurse calls ( < 0.0002). Questionnaire and 6-minute walk test scores at baseline vs last follow-up were 45.4 vs 48.4 ( = 0.48) and 364.4 vs 402.8 m ( = 0.58), respectively. Mean PAP at baseline vs follow-up was 31.5 vs 24.8 mm Hg ( = 0.005). NYHA class improved by at least one class in 85% of patients. Mean measurable HF-related spending preimplantation was CAD$29,814 per patient per year and postimplantation was CAD$25,642 per patient per year (including device cost).

CONCLUSIONS

PAP monitoring demonstrated reductions in HFHs, and emergency room and heart function clinic visits, with improvements in NYHA class. Although further economic evaluation is needed, these results support the use of PAP monitoring as an effective and cost-neutral tool in HF management in appropriately selected patients in a publicly funded healthcare system.

摘要

背景

肺动脉压(PAP)监测可减少心力衰竭(HF)住院次数(HFHs),并改善纽约心脏协会(NYHA)III级HF患者的生活质量。我们评估了PAP监测对加拿大门诊HF队列患者的预后和医疗支出的影响。

方法

20例NYHA III级HF患者在艾伯塔省卡尔加里市山麓医疗中心接受了无线PAP植入术。收集患者的实验室参数、血流动力学、6分钟步行试验和堪萨斯城心肌病问卷评分的基线数据,以及术后3、6、9和12个月的评估数据。从行政数据库中收集植入术前1年和术后1年的医疗费用。

结果

平均年龄为70.6岁;45%为女性。结果如下:急诊就诊次数减少88%(P = 0.0009);HFHs减少87%(P < 0.0003);心脏功能门诊就诊次数减少29%(P = 0.033),护士呼叫次数增加178%(P < 0.0002)。基线时与末次随访时的问卷评分和6分钟步行试验评分分别为45.4对48.4(P = 0.48)和364.4对402.8米(P = 0.58)。基线时与随访时的平均PAP分别为31.5对24.8 mmHg(P = 0.005)。85%的患者NYHA分级至少改善了一级。植入术前与术后每位患者每年与HF相关的可测量平均支出分别为29,814加元和25,642加元(包括设备成本)。

结论

PAP监测显示HFHs、急诊就诊次数和心脏功能门诊就诊次数减少,NYHA分级改善。尽管需要进一步的经济评估,但这些结果支持在公共资助的医疗系统中,将PAP监测作为一种有效且成本中性的工具,用于适当选择的HF患者的管理。