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保留乳头乳晕复合体与肥胖症——分阶段成功。

Nipple-areola-complex preservation and obesity-Successful in stages.

机构信息

Division of Plastic and Reconstructive Surgery Medicine, Stanford University School of Medicine, Palo Alto, California, USA.

Division of General Surgery, Stanford University Medical Center, Stanford, California, USA.

出版信息

Microsurgery. 2024 Jan;44(1):e31043. doi: 10.1002/micr.31043. Epub 2023 Apr 3.

Abstract

BACKGROUND

The superiority of nipple-sparing mastectomy (NSM) on breast aesthetics and patient-reported outcomes has previously been demonstrated. Despite 42.4% of adults in the United States being considered obese, obesity has been considered a contraindication to NSM due to concerns for nipple areolar complex (NAC) malposition or ischemic complications. This report investigates the feasibility and safety of a staged surgical approach to NSM with immediate microsurgical breast reconstruction in the high-risk obese population.

METHODS

Only patients with a body mass index (BMI) of >30 kg/m who underwent bilateral mastopexy or breast reduction for correction of ptosis or macromastia (stage 1), respectively, followed by bilateral prophylactic NSM with immediate microsurgical breast reconstruction with free abdominal flaps (stage 2) were included in the analysis. Patient demographics and surgical outcomes were analyzed.

RESULTS

Fifteen patients with high-risk genetic mutations for breast cancer with a mean age and BMI of 41.3 years and 35.0 kg/m , respectively, underwent bilateral staged NSM with immediate microsurgical breast reconstruction (30 breast reconstructions). At a mean follow-up of 15.7 months, complications were encountered following stage 2 only and included mastectomy skin necrosis (5 breasts [16.7%]), NAC necrosis (2 breasts [6.7%]), and abdominal seroma (1 patient [6.7%]) all of which were considered minor and neither required surgical intervention nor admission.

CONCLUSIONS

Implementation of a staged approach permits NAC preservation in obese patients who present for prophylactic mastectomy and immediate microsurgical reconstruction.

摘要

背景

乳头保留乳房切除术(NSM)在乳房美容和患者报告结果方面具有优势,这已得到先前的证明。尽管美国有 42.4%的成年人被认为是肥胖的,但由于担心乳头乳晕复合体(NAC)位置不正或缺血性并发症,肥胖被认为是 NSM 的禁忌症。本报告研究了在高风险肥胖人群中采用分期手术方法进行 NSM 并立即进行显微乳房重建的可行性和安全性。

方法

仅纳入 BMI>30kg/m 的患者,这些患者分别因乳房下垂或巨乳症而行双侧乳房提升术或乳房缩小术(第 1 阶段),然后行双侧预防性 NSM 并立即用游离腹部皮瓣进行显微乳房重建(第 2 阶段)。分析患者的人口统计学和手术结果。

结果

15 名具有乳腺癌高风险遗传突变的患者,平均年龄和 BMI 分别为 41.3 岁和 35.0kg/m ,接受了双侧分期 NSM 并立即进行显微乳房重建(30 例乳房重建)。平均随访 15.7 个月后,仅在第 2 阶段出现并发症,包括乳房切除术皮肤坏死(5 例乳房[16.7%])、NAC 坏死(2 例乳房[6.7%])和腹部血清肿(1 例患者[6.7%]),均被认为是轻微的,均无需手术干预或住院治疗。

结论

分期方法的实施允许为接受预防性乳房切除术和立即进行显微乳房重建的肥胖患者保留 NAC。

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