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住院吸入性肺炎患者行走能力下降的危险因素。

Risk factors for decreased walking ability in hospitalized patients with aspiration pneumonia.

机构信息

Department of Physical Therapy, School of Health Science, Toyohashi Sozo University, Toyohashi, Japan.

Department of Rehabilitation, Seirei Mikatahara General Hospital, Hamamatsu, Japan.

出版信息

J Int Med Res. 2023 Apr;51(4):3000605231163708. doi: 10.1177/03000605231163708.

Abstract

OBJECTIVE

To evaluate the factors that influence walking ability in patients hospitalized due to aspiration pneumonia.

METHODS

This retrospective observational study evaluated patients hospitalized with aspiration pneumonia. The primary endpoint was preservation of walking ability. Univariate and multivariate logistic regression analyses were performed with the preservation of walking ability as the dependent variable.

RESULTS

A total of 143 patients were enrolled in this study. The patients were divided into two groups: those whose walking ability decreased after hospitalization ( = 61) and those whose walking ability was maintained after hospitalization ( = 82). Multivariate logistic regression analyses showed that A-DROP (odds ratio [OR] 3.006; 95% confidence interval [CI] 1.452, 6.541;  < 0.01), the Geriatric Nutritional Risk Index (OR 0.919; 95% CI 0.875, 0.960; 0.001) and days to initial mobilization (OR 1.221; 95% CI 1.036, 1.531; 0.05) were the independent early predictors for preservation of walking ability.

CONCLUSION

Nutritional status and early mobilization were important risk factors affecting the maintenance of walking ability in patients hospitalized due to aspiration pneumonia. Thus, a combination of nutrition and early rehabilitation is needed for these patients.

REGISTRY OF RESEARCH STUDIES INVOLVING HUMAN SUBJECTS

This study was registered with the University Hospital Medical Information Network Clinical Trial Registry (UMIN 000046923).

摘要

目的

评估影响因吸入性肺炎住院患者行走能力的因素。

方法

本回顾性观察性研究纳入了因吸入性肺炎住院的患者。主要终点为保留行走能力。将保留行走能力作为因变量进行单因素和多因素逻辑回归分析。

结果

共纳入 143 例患者。患者分为两组:住院后行走能力下降组(n=61)和住院后行走能力保持组(n=82)。多因素逻辑回归分析显示,A-DROP(比值比 [OR] 3.006;95%置信区间 [CI] 1.452,6.541;P<0.01)、老年营养风险指数(OR 0.919;95%CI 0.875,0.960;P=0.001)和首次开始活动的天数(OR 1.221;95%CI 1.036,1.531;P=0.05)是保留行走能力的独立早期预测因素。

结论

营养状况和早期活动是影响吸入性肺炎住院患者行走能力维持的重要危险因素。因此,这些患者需要进行营养和早期康复相结合的治疗。

研究注册

本研究在大学医院医疗信息网临床试验注册中心(UMIN 000046923)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0743/10084548/6c7b2bfee918/10.1177_03000605231163708-fig1.jpg

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