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额颞部巨大硬膜外皮样囊肿:病例展示

Frontotemporal giant extradural dermoid cyst: illustrative case.

作者信息

Cao Dan, Xu Houyun, Hu Jibo, Mo Jun, Yu Xiping, Wang Junli, Hu Hongjie

机构信息

Departments of1Radiology.

2Neurosurgery, and.

出版信息

J Neurosurg Case Lessons. 2023 Apr 3;5(14). doi: 10.3171/CASE22547.

Abstract

BACKGROUND

Dermoid cyst is a rare benign tumor exhibiting a typical radiological pattern and most commonly located along the midline. Laboratory examination was always normal. However, the features of some rare cases are atypical that can be easily misdiagnosed as other tumors.

OBSERVATIONS

A 58-year-old patient presented with tinnitus, dizziness, blurred vision, and gait unsteadiness. Laboratory examination showed the serum levels of carbohydrate antigen 19-9 (CA19-9) were significantly increased (186 U/mL). A computed tomography (CT) scan revealed a predominant hypodense lesion in the left frontotemporal region with a hyperdense mural nodule. The lesion appeared as an intracranial extradural mass with a mural nodule on the sagittal image, displaying mixed signal on T1- and T2-weighted imaging. A left frontotemporal craniotomy was performed for cyst resection. Histological results confirmed a diagnosis of dermoid cyst. No tumor recurrences were observed at the 9-month follow-up.

LESSONS

Extradural dermoid cyst with a mural nodule is extremely rare. When a hypodense lesion on CT shows mixed signal on T1- and T2-weighted imaging with a mural nodule, even if it is located in the extradural areas, it is important to consider a dermoid cyst. Serum CA19-9 combined with atypical imaging features may contribute to the diagnosis of dermoid cysts. Only recognition of atypical radiological features can avoid misdiagnosis.

摘要

背景

皮样囊肿是一种罕见的良性肿瘤,具有典型的放射学表现,最常见于中线部位。实验室检查通常正常。然而,一些罕见病例的特征不典型,容易被误诊为其他肿瘤。

观察结果

一名58岁患者出现耳鸣、头晕、视力模糊和步态不稳。实验室检查显示血清糖类抗原19-9(CA19-9)水平显著升高(186 U/mL)。计算机断层扫描(CT)显示左额颞叶区域有一个主要的低密度病变,伴有一个高密度壁结节。在矢状位图像上,该病变表现为颅内硬膜外肿块并伴有壁结节,在T1加权和T2加权成像上呈混合信号。行左额颞开颅术切除囊肿。组织学结果证实为皮样囊肿。9个月的随访中未观察到肿瘤复发。

经验教训

伴有壁结节的硬膜外皮样囊肿极为罕见。当CT上的低密度病变在T1加权和T2加权成像上显示混合信号并伴有壁结节时,即使位于硬膜外区域,考虑皮样囊肿也很重要。血清CA19-9结合非典型影像学特征可能有助于皮样囊肿的诊断。只有认识到非典型放射学特征才能避免误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec7/10555548/5a363dd2998c/CASE22547f1.jpg

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