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荷兰人类猴痘传播的时间尺度。

Time Scales of Human Mpox Transmission in The Netherlands.

机构信息

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Center for Marine Environmental Studies, Ehime University, Ehime, Japan.

出版信息

J Infect Dis. 2024 Mar 14;229(3):800-804. doi: 10.1093/infdis/jiad091.

Abstract

Mpox has spread rapidly to many countries in nonendemic regions. After reviewing detailed exposure histories of 109 pairs of mpox cases in the Netherlands, we identified 34 pairs where transmission was likely and the infectee reported a single potential infector with a mean serial interval of 10.1 days (95% credible interval, 6.6-14.7 days). Further investigation into pairs from 1 regional public health service revealed that presymptomatic transmission may have occurred in 5 of 18 pairs. These findings emphasize that precaution remains key, regardless of the presence of recognizable symptoms of mpox.

摘要

猴痘已迅速传播到许多非流行地区的国家。在回顾了荷兰 109 对猴痘病例的详细接触史后,我们确定了 34 对可能发生传播的病例,受感染者报告了一个单一的潜在感染者,平均潜伏期为 10.1 天(95%可信区间为 6.6-14.7 天)。对来自 1 个地区公共卫生服务机构的病例对的进一步调查显示,18 对中有 5 对可能发生了症状前传播。这些发现强调,无论是否出现可识别的猴痘症状,预防仍然是关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d2/10938196/2c9c7873cc43/jiad091f1.jpg

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