Thiemke W A, Nathan D M
J Clin Microbiol. 1978 Dec;8(6):769-71. doi: 10.1128/jcm.8.6.769-771.1978.
Two simultaneous Klebsiella pneumoniae outbreaks resistant to multiple antibiotics are reported. The closely related strains were distinguished by comparing the zone diameters obtained by disk diffusion susceptibility testing but not by interpretations of susceptible, resistant, or intermediate. Similar conclusions were made when minimal inhibitory concentrations were considered. The separation was subsequently confirmed by capsular serotyping into types 2 and 30. The data presented suggest that routine antimicrobial susceptibility patterns obtained from disk diffusion and/or minimal inhibitory concentrations may serve as an inexpensive and reliable typing system for epidemiological investigations.
据报道,同时发生了两起对多种抗生素耐药的肺炎克雷伯菌暴发。通过比较纸片扩散法药敏试验获得的抑菌圈直径区分密切相关菌株,但不是通过敏感、耐药或中介的判定。考虑最低抑菌浓度时也得出了类似结论。随后通过荚膜血清分型确认为2型和30型。所呈现的数据表明,从纸片扩散法和/或最低抑菌浓度获得的常规抗菌药敏模式可作为一种廉价且可靠的分型系统用于流行病学调查。