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2 型糖尿病患者在基层医疗保健中反复开具睡眠药物处方:基于真实世界登记数据的观察性研究。

Recurrent prescription of sleep medication among primary care patients with type 2 diabetes: an observational study of real-world registry data.

机构信息

Rovaniemi Health Center, Koskikatu 25, Rovaniemi, 96200, Finland.

Research Unit of Population Health, University of Oulu, PO Box 5000, Oulu, 90015, Finland.

出版信息

BMC Prim Care. 2023 Apr 5;24(1):90. doi: 10.1186/s12875-023-02045-1.

DOI:10.1186/s12875-023-02045-1
PMID:37016350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10074898/
Abstract

BACKGROUND

Little knowledge exists on the prevalence of recurrent sleep medication prescriptions among primary care patients with type 2 diabetes (T2D). Our aims were to examine the prevalence of recurrent sleep medication prescriptions and to elucidate the most often prescribed sleep medications in a Finnish primary care T2D population.

METHODS

The study examined 4,508 T2D patients who consulted a primary health care center between 2011 and 2019 in Rovaniemi, Finland. All the data were retrieved from patient records, and recurrent sleep medication was defined as two or more prescriptions within the study period. We used the Chi-square and Kruskal-Wallis tests to compare patients who did and did not have recurrent sleep medication prescriptions.

RESULTS

Altogether 28.1% of the T2D patients had been prescribed recurrent sleep medication. Benzodiazepine-like medication, melatonin, and mirtazapine were most often prescribed (to 56.9%, 44.4%, and 35.8%, respectively). Only 22.0% of the patients with recurrent sleep medication prescriptions had been diagnosed with a sleep disorder.

CONCLUSIONS

Recurrent sleep medication prescriptions are frequent among primary care T2D patients. It seems that sleep disorders are underdiagnosed in relation to this. Primary care clinicians should carefully estimate the need for sleep medication when treating T2D patients' sleep problems and emphasize the diagnostic patterns of sleep problems.

摘要

背景

关于 2 型糖尿病(T2D)患者在初级保健中重复开具睡眠药物的情况,目前知之甚少。我们的目的是检查芬兰初级保健 T2D 人群中重复开具睡眠药物的情况,并阐明最常开具的睡眠药物。

方法

本研究调查了 2011 年至 2019 年期间在芬兰罗瓦涅米的一个初级保健中心就诊的 4508 名 T2D 患者。所有数据均从患者记录中检索,重复开具睡眠药物定义为在研究期间开具两次或两次以上的处方。我们使用卡方检验和克鲁斯卡尔-沃利斯检验比较了有和没有重复开具睡眠药物处方的患者。

结果

共有 28.1%的 T2D 患者被开具了重复的睡眠药物。苯二氮䓬类药物、褪黑素和米氮平是最常被开具的药物(分别为 56.9%、44.4%和 35.8%)。仅有 22.0%的重复开具睡眠药物处方的患者被诊断为睡眠障碍。

结论

重复开具睡眠药物处方在 T2D 患者中很常见。这表明睡眠障碍的诊断不足。初级保健临床医生在治疗 T2D 患者的睡眠问题时应仔细评估对睡眠药物的需求,并强调睡眠问题的诊断模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/064e/10074898/6bd193e3b4b8/12875_2023_2045_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/064e/10074898/6bd193e3b4b8/12875_2023_2045_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/064e/10074898/6bd193e3b4b8/12875_2023_2045_Figa_HTML.jpg

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