哺乳期大鼠肾脏近端曲管对液体的重吸收
Fluid reabsorption by the proximal convoluted tubule of the kidney in lactating rats.
作者信息
Arthur S K, Green R
出版信息
J Physiol. 1986 Feb;371:267-75. doi: 10.1113/jphysiol.1986.sp015973.
Using free-flow micropuncture techniques, the rate of reabsorption from the proximal convoluted tubules was measured in virgin, 19-day-pregnant and 6- to 7-day-lactating Sprague-Dawley rats. In separate groups of animals proximal convoluted tubules were filled with silicone rubber, dissected out and their lengths measured. Single nephron glomerular rate was increased in pregnant and lactating animals. The rate of reabsorption per unit length of the proximal convoluted tubule was decreased in pregnant animals but similar in virgins and lactating rats. The proximal convoluted tubule was increased in length in pregnant and lactating animals. As a result the total reabsorption by the proximal convoluted tubule was similar in virgin and pregnant animals but increased in lactating animals. The amount reabsorbed by the loop of Henle and distal parts of the nephron is greater in pregnant and lactating animals than in virgins.
运用自由流动微穿刺技术，对未孕、妊娠19天以及泌乳6至7天的斯普拉格-道利大鼠近端曲管的重吸收速率进行了测量。在不同组动物中，将近端曲管用硅橡胶填充，解剖取出并测量其长度。妊娠和泌乳动物的单肾单位肾小球滤过率增加。妊娠动物近端曲管单位长度的重吸收速率降低，但未孕和泌乳大鼠相似。妊娠和泌乳动物的近端曲管长度增加。因此，近端曲管的总重吸收在未孕和妊娠动物中相似，但在泌乳动物中增加。妊娠和泌乳动物髓袢及肾单位远端部分的重吸收量比未孕动物多。
Zotero 插件