Eisenberg R S, Gage P W
J Gen Physiol. 1969 Mar;53(3):279-97. doi: 10.1085/jgp.53.3.279.
The resting ionic conductances of frog sartorius muscle fibers have been determined in a variety of conditions in order to measure the potassium conductance of the tubular and surface membranes (gK(t) and gK(s)) and the chloride conductance of the tubular and surface membranes (gCl(t) and gCl(s)). In both normal fibers and fibers without tubules, measurements of input resistance and diameter were made at normal pH and at low pH when the chloride conductance was very small. These measurements permitted the separation of the ionic conductances: gCl(s) = 219 micromhos/cm(2); gCl(t) = 0 micromhos/cm(2); gK(s) = 28 micromhos/cm(2); gK(t) = 55 micromhos/cm(2). Possible sources of systematic error are discussed and a statistical analysis of the effects of random error is presented. The implications of the nonuniformity of membrane properties are discussed along with possible anatomical explanations.
为了测量管状膜和表面膜的钾电导（gK(t) 和 gK(s)）以及管状膜和表面膜的氯电导（gCl(t) 和 gCl(s)），已在多种条件下测定了青蛙缝匠肌纤维的静息离子电导。在正常纤维和无管状结构的纤维中，当氯电导非常小时，在正常pH值和低pH值下测量输入电阻和直径。这些测量允许分离离子电导：gCl(s) = 219微西门子/平方厘米；gCl(t) = 0微西门子/平方厘米；gK(s) = 28微西门子/平方厘米；gK(t) = 55微西门子/平方厘米。讨论了系统误差的可能来源，并对随机误差的影响进行了统计分析。还讨论了膜特性不均匀性的影响以及可能的解剖学解释。
