Department of Women's and Children's Health, Otago Medical School, University of Otago, Dunedin, New Zealand.
New Zealand Pharmacovigilance Centre, Division of Health Sciences, University of Otago, Dunedin, New Zealand.
Aust N Z J Obstet Gynaecol. 2023 Jun;63(3):441-447. doi: 10.1111/ajo.13672. Epub 2023 Apr 4.
The combined oral contraceptive (COC) is the most commonly used hormonal contraceptive in Aotearoa New Zealand (Aotearoa/NZ). Currently there is limited data available on who uses COC in Aotearoa/NZ. The aims were to (i) define the population of reproductive-aged females in Aotearoa/NZ in 2018 and identify the rate of COC use among this group and (ii) describe the sociodemographic and geographic characteristics of the population of COC users compared to the general population of reproductive-aged females in 2018.
This whole-of-population cross-sectional study used the Integrated Data Infrastructure, a large research database managed by Statistics New Zealand. Females aged 16-50 years with complete sociodemographic and geographic information in 2018 from Aotearoa/NZ's estimated resident population were included. COC dispensing records to this cohort were identified from the national Pharmaceutical Collection. This paper reports descriptive counts of COC use and employs generalised linear regression with a binomial distribution and a log link to estimate adjusted risk ratios (aRR) of COC use for key sociodemographic and geographic subgroups.
Of 1 113 750 individuals in the study, 159 789 (14.3%) were dispensed as COC in 2018. European/other individuals were most likely to use COC (aRR: 2.72, 2.67-2.78), and Pacific Peoples were least likely (aRR: 0.56, 0.55-0.58) to use COC. Individuals residing in the most deprived quintile had less COC use than individuals in the least deprived quintile (aRR: 0.73, 0.72-0.74).
Our study is able to highlight significant disparities in use by ethnicity, area-level deprivation, and geographic factors.
复方口服避孕药（COC）是新西兰（新西兰）最常用的激素避孕药。目前，关于新西兰谁在使用 COC 的数据有限。目的是：（i）定义 2018 年新西兰生殖年龄女性的人口，并确定该人群中 COC 的使用率；（ii）描述与 2018 年生殖年龄女性普通人群相比，COC 使用者的社会人口统计学和地理特征。
这项全人群横断面研究使用了综合数据基础设施，这是一个由新西兰统计局管理的大型研究数据库。该研究纳入了 2018 年新西兰估计常住人口中年龄在 16-50 岁之间、具有完整社会人口统计学和地理信息的女性。从全国药品收集中确定了该队列的 COC 配药记录。本文报告了 COC 使用的描述性计数，并使用二项分布和对数链接的广义线性回归来估计 COC 使用的关键社会人口统计学和地理亚组的调整风险比（aRR）。
在研究的 1113750 名个体中，2018 年有 159789 人（14.3%）被配给 COC。欧洲/其他族裔的人最有可能使用 COC（aRR：2.72，2.67-2.78），而太平洋族裔的人最不可能使用 COC（aRR：0.56，0.55-0.58）。生活在最贫困五分位数的个体使用 COC 的比例低于生活在最不贫困五分位数的个体（aRR：0.73，0.72-0.74）。
我们的研究能够突出显示种族、地区贫困程度和地理因素方面使用的显著差异。
