用于在活细胞和斑马鱼中成像硫化氢（HS）的双光子荧光探针的开发。
Development of a two-photon fluorescent probe for imaging hydrogen sulfide (HS) in living cells and zebrafish.
作者信息
Xu Chen, Zhang Yukun, Sun Hui, Ai Jindong, Ren Mingguang
机构信息
State Key Laboratory of Biobased Material and Green Papermaking, Key Laboratory of Pulp & Paper Science and Technology of Shandong Province/Ministry of Education, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
出版信息
Anal Methods. 2023 Apr 27;15(16):1948-1952. doi: 10.1039/d3ay00375b.
We present a new two-photon fluorescent probe (T-HS) for the detection of HS. With the addition of hydrogen sulfide, the absorption and fluorescence spectra of the probe show regular changes. The probe exhibited favorable properties, such as large turn-on fluorescence signal, good selectivity and low cytotoxicity. Moreover, the probe T-HS was successfully used for the fluorescence imaging of HS in live cells and zebrafish.
我们提出了一种用于检测硫化氢（HS）的新型双光子荧光探针（T-HS）。加入硫化氢后，该探针的吸收光谱和荧光光谱呈现出规律性变化。该探针具有良好的性能，如大的荧光开启信号、良好的选择性和低细胞毒性。此外，探针T-HS已成功用于活细胞和斑马鱼中硫化氢的荧光成像。
Zotero 插件