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探索微生物组与神经递质之间的联系。

Toward understanding links between the microbiome and neurotransmitters.

机构信息

Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, California, USA.

Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

出版信息

Ann N Y Acad Sci. 2023 Jun;1524(1):10-16. doi: 10.1111/nyas.14993. Epub 2023 Apr 5.

DOI:10.1111/nyas.14993
PMID:37017112
Abstract

The gut microbiota modulates neurobiological activity in various animal lineages. This is often proposed to occur through interactions with neurotransmitters and other neuromodulatory molecules in the host. Our commentary will discuss recent research that establishes microbiota-neurotransmitter connections, gaps in current understanding, and outstanding questions that may guide future advances in the field of microbiota-nervous system interactions.

摘要

肠道微生物群调节各种动物谱系中的神经生物学活动。这通常被认为是通过与宿主中的神经递质和其他神经调质分子相互作用来实现的。我们的评论将讨论最近的研究,这些研究确立了微生物群-神经递质的联系、当前理解中的差距以及可能指导该领域未来进展的悬而未决的问题。

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