Shakya S, Shrestha B, Singh J, Ranjit S
Department of Anesthesiology, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Kathmandu Univ Med J (KUMJ). 2022 Apr-Jun;20(78):171-177.
Background Hypotension after induction of general anesthesia (GA) is common due to pre-existing hypovolemia and has adverse effects on organ function. Out of several methods to predict post-induction hypotension, nowadays Inferior Vena Cava: Aorta (IVC: Ao) index has been studied with different cut-off values. However, limited studies have been performed in our part of the world. Objective To evaluate the efficacy of pre-induction Inferior Vena Cava: Aorta index with a cutoff value of 1.0 for predicting the occurrence of post-induction hypotension after general anesthesia in the Nepalese population. Method A total of 100 patients of ASA I and II, aged more than 18 years posted for elective surgeries under general anesthesia were enrolled in this cross-sectional, observational study. Ultrasonographic guided Inferior Vena Cava: Aorta index was calculated and based on a cut-off value of 1.0, two groups were formed. Seventy patients in group A with Inferior Vena Cava: Aorta index less than 1.0 and 30 patients in group B with Inferior Vena Cava: Aorta index more than 1.0 were enrolled. Vitals parameters were recorded every minute for five minutes after induction of general anesthesia. Incidence of hypotension was the primary outcome. Statistical analysis was done using student t-test, ANOVA test and Chi-square test. Result Inferior Vena Cava: Aorta index with cut-off value of 1.0 predicted post-induction hypotension with excellent efficacy. Total 65 patients developed post-induction hypotension, out of which 63 patients had Inferior Vena Cava: Aorta index less than 1.0. Conclusion We concluded that pre-induction Inferior Vena Cava: Aorta index with cut-off value of 1.0 have high diagnostic accuracy with high degree of sensitivity and specificity to predict hypotension after induction of general anesthesia.
由于术前存在血容量不足,全身麻醉(GA)诱导后低血压很常见,且对器官功能有不良影响。在几种预测诱导后低血压的方法中,目前下腔静脉:主动脉(IVC:Ao)指数已采用不同的临界值进行研究。然而,在我们这个地区进行的研究有限。目的:评估术前下腔静脉:主动脉指数临界值为1.0时,预测尼泊尔人群全身麻醉后诱导后低血压发生情况的有效性。方法:本横断面观察性研究共纳入100例年龄超过18岁、拟行全身麻醉下择期手术的ASA I级和II级患者。计算超声引导下的下腔静脉:主动脉指数,并根据临界值1.0分为两组。A组70例患者下腔静脉:主动脉指数小于1.0,B组30例患者下腔静脉:主动脉指数大于1.0。全身麻醉诱导后每分钟记录生命体征参数,共记录5分钟。低血压发生率为主要观察指标。采用学生t检验、方差分析和卡方检验进行统计分析。结果:临界值为1.0的下腔静脉:主动脉指数预测诱导后低血压的效果极佳。共有65例患者发生诱导后低血压,其中63例患者下腔静脉:主动脉指数小于1.0。结论:我们得出结论,术前临界值为1.0的下腔静脉:主动脉指数对预测全身麻醉诱导后低血压具有较高的诊断准确性、高灵敏度和特异性。