丙磺舒诱发的免疫性溶血性贫血。
Probenecid induced immune hemolytic anemia.
作者信息
Kickler T S, Buck S, Ness P, Shirey R S, Sholar P W
出版信息
J Rheumatol. 1986 Feb;13(1):208-9.
PMID:3701734
Abstract
We report a patient who, while receiving probenecid and colchicine for acute gouty arthritis, developed severe hemolytic anemia in association with a generalized rash. The hemolysis was immune mediated as shown by a positive direct Coombs' test. In vitro hematologic studies showed that a probenecid dependent antibody was present.
摘要
我们报告了一名患者，该患者在接受丙磺舒和秋水仙碱治疗急性痛风性关节炎时，出现了严重的溶血性贫血并伴有全身性皮疹。直接抗人球蛋白试验阳性表明溶血是由免疫介导的。体外血液学研究显示存在一种依赖丙磺舒的抗体。
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