[多发性骨髓瘤和慢性淋巴细胞白血病中的低丙种球蛋白血症与免疫缺陷]
[Hypogammaglobulinemia and immunodeficiency in multiple myeloma and chronic lymphoid leukemia].
作者信息
Matthes Thomas, Jandus Peter
机构信息
Service d'hématologie, Département d'oncologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Service d'immunologie et allergologie, Département de médecine, Hôpitaux universitaires de Genève, 1211 Genève 14.
出版信息
Rev Med Suisse. 2023 Apr 5;19(821):668-673. doi: 10.53738/REVMED.2023.19.821.668.
Infections are among the leading causes of morbidity and mortality in lymphoproliferative malignancies such as multiple myeloma (MM) and chronic lymphocytic leukemia (CLL). The causes of infections are often multifactorial and may be due to disease- or treatment-related factors. New therapies have improved survival in lymphoproliferative malignancies, resulting in an increased incidence of secondary immune deficiencies (SID) in these diseases.
感染是多发性骨髓瘤（MM）和慢性淋巴细胞白血病（CLL）等淋巴增殖性恶性肿瘤发病和死亡的主要原因之一。感染的原因通常是多因素的，可能与疾病或治疗相关因素有关。新疗法提高了淋巴增殖性恶性肿瘤的生存率，导致这些疾病中继发性免疫缺陷（SID）的发病率增加。
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