Department of Heavy Particle Medical Science, Graduate School of Medical Science, Yamagata University, Iidanishi, Yamagata, Japan.
Department of Radiation Oncology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
J Appl Clin Med Phys. 2023 May;24(5):e13987. doi: 10.1002/acm2.13987. Epub 2023 Apr 5.
The errors on the stopping power ratio (SPR) of mouthpiece samples from ERKODENT were evaluated. Erkoflex and Erkoloc-pro from ERKODENT and samples that combined Erkoflex and Erkoloc-pro were computed tomography (CT)-scanned using head and neck (HN) protocol at the East Japan Heavy Ion Center (EJHIC), and the values were averaged to obtain the CT number. The integral depth dose of the Bragg curve with and without these samples was measured for 292.1, 180.9, and 118.8 MeV/u of the carbon-ion pencil beam using an ionization chamber with concentric electrodes at the horizontal port of the EJHIC. The average value of the water equivalent length (WEL) of each sample was obtained from the difference between the range of the Bragg curve and the thickness of the sample. To calculate the difference between the theoretical and measured values, the theoretical CT number and SPR value of the sample were calculated using the stoichiometric calibration method. Compared with the Hounsfield unit (HU)-SPR calibration curve used at the EJHIC, the SPR error on each measured and theoretical value was calculated. The WEL value of the mouthpiece sample had an error of approximately 3.5% in the HU-SPR calibration curve. From this error, it was evaluated that for a mouthpiece with a thickness of 10 mm, a beam range error of approximately 0.4 mm can occur, and for a mouthpiece with a thickness of 30 mm, a beam range error of approximately 1 mm can occur. For a beam passing through the mouthpiece in HN treatment, it would be practical to consider a mouthpiece margin of 1 mm to avoid beam range errors if ions pass through the mouthpiece.
评估了 ERKODENT 口内片的阻止本领比 (SPR) 误差。使用头部和颈部 (HN) 协议在东日本离子中心 (EJHIC) 对 ERKODENT 的 Erkoflex 和 Erkoloc-pro 以及将 Erkoflex 和 Erkoloc-pro 组合在一起的样品进行了计算机断层扫描 (CT) 扫描,并对这些值进行了平均以获得 CT 数。使用同心电极电离室在 EJHIC 的水平端口处测量了具有和不具有这些样品的 Bragg 曲线的积分深度剂量,对于 292.1、180.9 和 118.8 MeV/u 的碳离子铅笔束。从 Bragg 曲线的射程和样品厚度之间的差值获得每个样品的水当量长度 (WEL) 的平均值。为了计算理论值和测量值之间的差异,使用化学计量校准方法计算了样品的理论 CT 数和 SPR 值。与 EJHIC 中使用的亨氏单位 (HU)-SPR 校准曲线相比,计算了每个测量值和理论值的 SPR 误差。口内片样品在 HU-SPR 校准曲线上的 WEL 值存在约 3.5%的误差。从这个误差可以评估,对于厚度为 10 毫米的口内片,束流射程误差约为 0.4 毫米,而对于厚度为 30 毫米的口内片,束流射程误差约为 1 毫米。对于穿过 HN 治疗中的口内片的光束,如果离子穿过口内片,为了避免束流射程误差,考虑口内片边缘为 1 毫米是实际的。