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EClinicalMedicine. 2020 Jun 26;24:100433. doi: 10.1016/j.eclinm.2020.100433. eCollection 2020 Jul.
2
[Seroprevalence of anti-Mycoplasma pneumoniae antibodies in otherwise healthy children].
Rev Chil Pediatr. 2020 Jun;91(3):347-352. doi: 10.32641/rchped.v91i3.1476.
3
Human adenovirus Coinfection aggravates the severity of Mycoplasma pneumoniae pneumonia in children.人腺病毒合并感染加重儿童肺炎支原体肺炎的严重程度。
BMC Infect Dis. 2020 Jun 16;20(1):420. doi: 10.1186/s12879-020-05152-x.
4
Short-term relevance of lower respiratory viral coinfection in inpatients under 2 years of age.2岁以下住院患者下呼吸道病毒合并感染的短期相关性
An Pediatr (Engl Ed). 2018 Mar;88(3):127-135. doi: 10.1016/j.anpede.2017.03.006. Epub 2017 Jun 16.
5
Epidemiological and clinical analysis of community-acquired pneumonia in children from a Spanish population, 2010-2015.2010 - 2015年西班牙儿童社区获得性肺炎的流行病学与临床分析
An Pediatr (Engl Ed). 2019 Jul;91(1):21-29. doi: 10.1016/j.anpede.2019.01.003. Epub 2019 Feb 6.
6
Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study.中国浙江 36 例 2019 冠状病毒病(COVID-19)患儿的临床和流行病学特征:一项观察性队列研究。
Lancet Infect Dis. 2020 Jun;20(6):689-696. doi: 10.1016/S1473-3099(20)30198-5. Epub 2020 Mar 25.
7
Clinical characteristics of pneumonia caused by Mycoplasma pneumoniae in children of different ages.不同年龄段儿童肺炎支原体肺炎的临床特征
Int J Clin Exp Pathol. 2018 Feb 1;11(2):855-861. eCollection 2018.
8
The Clinical Presentation of Pediatric Mycoplasma pneumoniae Infections-A Single Center Cohort.儿童肺炎支原体感染的临床表现——一项单中心队列研究。
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9
Burden of Respiratory Syncytial Virus Disease and Mortality Risk Factors in Argentina: 18 Years of Active Surveillance in a Children's Hospital.阿根廷呼吸道合胞病毒疾病负担和死亡风险因素:儿童医院 18 年主动监测
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10
Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care.儿童重症监护病房收治的严重肺炎支原体感染。
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[住院儿童呼吸道样本中肺炎支原体的分子检测]

[Molecular detection of Mycoplasma pneumoniae in respiratory samples from hospitalized children].

作者信息

Pury Selene, Álvarez María Soledad, García Oro María Cecilia

机构信息

Servicio de Pediatría. Hospital Infantil. Córdoba, Argentina.

Servicio de Infectología. Hospital Infantil. Córdoba, Argentina.

出版信息

Rev Fac Cien Med Univ Nac Cordoba. 2023 Mar 31;80(1):20-24. doi: 10.31053/1853.0605.v80.n1.37514.

DOI:10.31053/1853.0605.v80.n1.37514
PMID:37018359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10142670/
Abstract

INTRODUCTION

It is currently reported that Mycoplasma pneumoniae (MP) infection can occur at a young age. Objective: Describe the findings of the molecular detection of MP in respiratory secretions of patients who required hospitalization due to acute respiratory infection, in a pediatric hospital.

POPULATION AND METHODS

Data collection was performed by reviewing medical records and statistical correlation using the chi-square test. 919 patients from one month to fourteen years and eleven months of age who required hospitalization for acute respiratory infection were included. The frequency by age and sex of the isolation of MP was analyzed together with other respiratory pathogens.

RESULTS

Mycoplasma pneumoniae was the most frequently detected microorganism (30%), followed by respiratory syncytial virus (RSV) (25.1%). Age and sex did not behave as a predictor of detection for MP. In 47.3% of the patients, MP was isolated together with another pathogen, the most prevalent was RSV 31.3%. Regarding the diagnoses at discharge of the group of patients with isolation of MP and a another microorganism, 50.8% had bronchiolitis, and in the group of patients with identification only of MP this percentage was 32.4%. The difference in the distributions was statistically significant (p <0.05).

CONCLUSION

We conclude that Mycoplasma pneumoniae detection is frequent in our environment and occurs in a significant number of cases together with another respiratory pathogen. These findings should prompt further study to determine their clinical relevance.

摘要

引言

目前有报道称肺炎支原体(MP)感染可发生于低龄人群。目的:描述在一家儿科医院因急性呼吸道感染住院的患者呼吸道分泌物中MP的分子检测结果。

研究对象与方法

通过查阅病历进行数据收集,并使用卡方检验进行统计相关性分析。纳入919例年龄从1个月至14岁11个月因急性呼吸道感染需住院治疗的患者。分析MP与其他呼吸道病原体分离的年龄和性别频率。

结果

肺炎支原体是最常检测到的微生物(30%),其次是呼吸道合胞病毒(RSV)(25.1%)。年龄和性别并非MP检测的预测因素。在47.3%的患者中,MP与另一种病原体同时被分离出来,最常见的是RSV(31.3%)。关于MP与另一种微生物分离的患者组出院诊断,50.8%患有细支气管炎,而仅鉴定出MP的患者组这一比例为32.4%。分布差异具有统计学意义(p<0.05)。

结论

我们得出结论,在我们的环境中肺炎支原体检测很常见,并且在大量病例中与另一种呼吸道病原体同时出现。这些发现应促使进一步研究以确定它们的临床相关性。