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静脉注射肾上腺素对猕猴血小板的影响。

Effects of intravenous epinephrine on macaque platelets.

作者信息

Beatty C H, Baughman W L, Caruso V, Howard C F

出版信息

J Med Primatol. 1986;15(1):49-61.

PMID:3701838
Abstract

Blood was obtained from three species of macaques for a study of platelets. A rapidly mobilizable platelet pool was demonstrated in rhesus macaques given intravenous epinephrine. The number of platelets/ml of blood increased about 30% 3 to 5 min after epinephrine was given. The size distributions of the platelets were similar before and after injection. Platelet aggregability was increased after injection. Basal platelet aggregabilities, as measured by platelet aggregate ratios, were similar in rhesus macaques. Celebes black macaques, and human subjects, but were significantly greater in cynomolgus macaques than in the other three species.

摘要

从三种猕猴身上采集血液用于血小板研究。给恒河猴静脉注射肾上腺素后,发现其存在一个可快速动员的血小板池。注射肾上腺素后3至5分钟,每毫升血液中的血小板数量增加了约30%。注射前后血小板的大小分布相似。注射后血小板聚集性增加。通过血小板聚集率测量的基础血小板聚集性在恒河猴、西里伯斯黑猴和人类受试者中相似,但食蟹猕猴的基础血小板聚集性显著高于其他三个物种。

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