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Multiscale model for blood flow after a bileaflet artificial aortic valve implantation.

作者信息

Nowak Marcin, Divo Eduardo, Adamczyk Wojciech P

机构信息

Gdańsk University of Technology, Faculty of Civil and Environmental Engineering, Department of Mechanics of Materials and Structures, Poland.

Mechanical Engineering Department, Embry-Riddle Aeronautical University, Orlando, FL, United States of America.

出版信息

Comput Biol Med. 2023 May;158:106805. doi: 10.1016/j.compbiomed.2023.106805. Epub 2023 Mar 24.

DOI:10.1016/j.compbiomed.2023.106805
PMID:37019010
Abstract

Cardiovascular diseases are the leading cause of mortality in the world, mainly due to atherosclerosis and its consequences. The article presents the numerical model of the blood flow through artificial aortic valve. The overset mesh approach was applied to simulate the valve leaflets motion and to realize the moving mesh, in the aortic arch and the main branches of cardiovascular system. To capture the cardiac system's response and the effect of vessel compliance on the outlet pressure, the lumped parameter model has been also included within the solution procedure. Three different turbulence modeling approaches were used and compared - the laminar, k-ϵ and k-ω model. The simulation results were also compared with the model excluding the moving valve geometry and the importance of the lumped parameter model for the outlet boundary condition was analyzed. Proposed numerical model and protocol was found as suitable for performing the virtual operations on the real patient vasculature geometry. The time-efficient turbulence model and overall solving procedure allows to support the clinicians in making decisions about the patient treatment and to predict the results of the future surgery.

摘要

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