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口腔色素病变。

Pigmented Lesions of the Oral Cavity.

机构信息

University of Kentucky College of Dentistry, 770 Rose Street, Lexington, KY 40536, USA.

University of Kentucky College of Dentistry, 770 Rose Street, Lexington, KY 40536, USA.

出版信息

Oral Maxillofac Surg Clin North Am. 2023 May;35(2):153-158. doi: 10.1016/j.coms.2022.10.008.

DOI:10.1016/j.coms.2022.10.008
PMID:37019502
Abstract

Pigmented lesions are a common finding in the oral cavity. Oral pigmented lesions may range from solitary to multiple, pinpoint to diffuse, and have a variety of clinical implications. Nearly all solitary pigmented lesions require a biopsy to rule out mucosal melanoma. Oral mucosal melanoma has a grim prognosis and early discovery is of utmost importance. Multiple pigmented lesions in the oral cavity may indicate a systemic condition about which the patient may not be aware. The presentation and management of these various lesions is the focus of this article.

摘要

口腔内的色素性病变较为常见。口腔色素性病变的表现可以是单发或多发、针尖样或弥漫性,其临床意义也多种多样。几乎所有的单发色素性病变都需要进行活检以排除黏膜黑色素瘤。口腔黏膜黑色素瘤的预后较差,因此早期发现至关重要。口腔内的多发性色素性病变可能提示患者存在某种尚未察觉的系统性疾病。本文主要介绍这些不同病变的临床表现和处理方法。

相似文献

1
Pigmented Lesions of the Oral Cavity.口腔色素病变。
Oral Maxillofac Surg Clin North Am. 2023 May;35(2):153-158. doi: 10.1016/j.coms.2022.10.008.
2
Melanin-associated pigmented lesions of the oral mucosa: presentation, differential diagnosis, and treatment.口腔黏膜色素相关病变:表现、鉴别诊断和治疗。
Dermatol Ther. 2010 May-Jun;23(3):220-9. doi: 10.1111/j.1529-8019.2010.01319.x.
3
Oral melanoma and other pigmentations: when to biopsy?口腔黑色素瘤和其他色素沉着:何时进行活检?
J Eur Acad Dermatol Venereol. 2018 Feb;32(2):209-214. doi: 10.1111/jdv.14574. Epub 2017 Sep 14.
4
Black and Brown Oro-facial Mucocutaneous Neoplasms.黑色和棕色口腔颌面部黏膜皮肤肿瘤
Head Neck Pathol. 2019 Mar;13(1):56-70. doi: 10.1007/s12105-019-01008-2. Epub 2019 Jan 29.
5
[Oral and perioral endogenous pigmented lesions].[口腔及口周内源性色素沉着病变]
Rev Med Chir Soc Med Nat Iasi. 2008 Oct-Dec;112(4):1054-60.
6
[Oral medicine 10. Pigmented lesions of the oral mucosa].[口腔医学10.口腔黏膜色素沉着病变]
Ned Tijdschr Tandheelkd. 2013 Oct;120(10):555-61.
7
Benign focal melanotic lesions of the oral mucosa.口腔黏膜良性局灶性黑素沉着病变
J Oral Med. 1984 Apr-Jun;39(2):91-6, 118.
8
Hutchinson's melanotic freckle in oral mucous membrane.口腔黏膜的哈钦森黑素雀斑。
Cancer. 1970 Aug;26(2):297-302. doi: 10.1002/1097-0142(197008)26:2<297::aid-cncr2820260209>3.0.co;2-o.
9
Solitary pigmented lesions in oral mucosa in Latin American children: A case series.拉丁美洲儿童口腔黏膜孤立性色素沉着病变:病例系列
Pediatr Dermatol. 2018 May;35(3):374-377. doi: 10.1111/pde.13465. Epub 2018 Mar 24.
10
Pigmented lesions of the oral cavity.口腔色素沉着病变
J Oral Surg. 1978 Dec;36(12):950-5.

引用本文的文献

1
Amelanotic Melanocytic Nevus of the Oral Cavity: A Case Report and Literature Review.口腔无色素性黑素细胞痣:一例报告及文献复习
Diagnostics (Basel). 2025 Jun 18;15(12):1554. doi: 10.3390/diagnostics15121554.
2
Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management.口腔黏膜色素沉着病变:临床表现、组织学及管理建议
Am J Clin Dermatol. 2025 May 14. doi: 10.1007/s40257-025-00950-y.
3
Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review.
口腔黏膜色素沉着病变的鉴别诊断:基于临床的概述与叙述性综述
Cancers (Basel). 2024 Jul 8;16(13):2487. doi: 10.3390/cancers16132487.