Azhmukhanbetova A Zh, Nikolaeva L F, Titov V N, Filippov I K, Markarian S S
Kardiologiia. 1986 Feb;26(2):61-7.
The study of patterns of serum AST, ALT, CPK, LDH, and glycogen phosphorylase (GP) activity following bicycle ergometry in 26 male patients 1 to 1.5 months after myocardial infarction demonstrated no increase in AST, ALT and CPK activity, whereas total LDH activity was increased, with a tendency to elevated LDH-1 and LDH-2 fractions, as compared to the baseline, in those cases where exercise was discontinued because of ST depression. Patients with favorable response to bicycle ergometry that continued until the submaximum heart rate for a given age was achieved showed a tendency to elevated LDH-5 that may be a physiological response to exercise. The demonstrated increase in total GP activity, both in patients with exercise-induced ST depression and in those with elevated ST from the leads corresponding to the site of myocardial infarction, may reflect stress-induced reversible ischemia.
对26名男性心肌梗死患者在发病1至1.5个月后进行自行车测力计运动后血清谷草转氨酶（AST）、谷丙转氨酶（ALT）、肌酸磷酸激酶（CPK）、乳酸脱氢酶（LDH）和糖原磷酸化酶（GP）活性模式的研究表明，AST、ALT和CPK活性没有增加，而总LDH活性增加，在因ST段压低而停止运动的病例中，与基线相比，LDH-1和LDH-2组分有升高趋势。对自行车测力计运动反应良好并持续运动至达到特定年龄次最大心率的患者显示LDH-5有升高趋势，这可能是对运动的生理反应。在运动诱发ST段压低的患者以及心肌梗死部位对应导联ST段抬高的患者中，所显示的总GP活性增加可能反映了应激诱导的可逆性缺血。
