Berdel D
Klin Padiatr. 1986 Mar-Apr;198(2):71-8. doi: 10.1055/s-2008-1026857.
Aetiological factors and mechanisms of bronchial hyperreactivity are discussed. The hypothesis of increased permeability of the bronchial mucosa--caused by either endogenous or exogenous stimuli--as the most plausible explanation for the connection between hyperreactivity and childhood asthma bronchiale is emphasized. Finally, unspecific inhalative provocation tests for proof of bronchial hyperreactivity, its indications and contraindications as well as the criteria of judgement are mentioned.
讨论了支气管高反应性的病因和机制。强调了支气管黏膜通透性增加的假说——由内源性或外源性刺激引起——作为高反应性与儿童支气管哮喘之间联系的最合理的解释。最后，提到了用于证明支气管高反应性的非特异性吸入激发试验、其适应证和禁忌证以及判断标准。
