Russi E
Schweiz Med Wochenschr. 1985 Apr 27;115(17):597-601.
Bronchial hyperreactivity is considered to play a major role in the pathogenesis of asthma. Airway reactivity can be reproducibly quantitated by bronchial provocation procedures. Various physical or chemical stimuli may be applied, and inhalational challenge with methacholine is becoming a routine test in pulmonary function laboratories. The indications for, and clinical value of, measurement of bronchial reactivity are described, and possible mechanisms of hyperreactivity are discussed.
支气管高反应性被认为在哮喘的发病机制中起主要作用。气道反应性可通过支气管激发试验进行重复性定量测定。可应用各种物理或化学刺激，而用乙酰甲胆碱进行吸入激发试验正成为肺功能实验室的常规检查。本文描述了支气管反应性测定的适应证和临床价值，并讨论了高反应性可能的机制。
