Kileny P, Shea S L
J Speech Hear Res. 1986 Mar;29(1):20-8. doi: 10.1044/jshr.2901.20.
Click and 500-Hz tone-burst thresholds were determined by four independent judges from sequentially recorded auditory brain stem responses--middle-latency responses (ABR-MLR)--and from 40-Hz event-related potentials (ERP) in 10 normal-hearing subjects. The thresholds determined from the two electrophysiologic methods were compared to each other and to behavioral pure-tone thresholds by means of matched-pair t tests (alpha less than or equal to .016 for each comparison). Thresholds estimated from both techniques closely approximated behavioral audiometric thresholds. The general trend was for the 40-Hz ERP thresholds to be lower than the MLR thresholds. However, the statistical analysis indicated that the differences between the two electrophysiologic thresholds and pure-tone audiometric thresholds were not significant. At threshold, the amplitudes of the 40-Hz ERPs were almost twice as large as the MLR amplitudes for clicks and only slightly larger than the MLR amplitudes for the 500-Hz tone-bursts. It was concluded that the MLR and the 40-Hz ERP techniques are equally viable procedures for threshold estimation in adults.
10名听力正常的受试者依次记录了听觉脑干反应——中潜伏期反应（ABR-MLR）以及40赫兹事件相关电位（ERP），由4名独立的评判员确定了点击声和500赫兹短纯音的阈值。通过配对t检验（每次比较α≤0.016），将两种电生理方法确定的阈值相互比较，并与行为纯音阈值进行比较。两种技术估计的阈值都非常接近行为听力测定阈值。一般趋势是40赫兹ERP阈值低于MLR阈值。然而，统计分析表明，两种电生理阈值与纯音听力测定阈值之间的差异并不显著。在阈值时，40赫兹ERP的振幅对于点击声几乎是MLR振幅的两倍，对于500赫兹短纯音仅略大于MLR振幅。得出的结论是，MLR和40赫兹ERP技术是成人阈值估计同样可行的方法。
