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利多卡因雾化与气道神经阻滞用于清醒纤维支气管镜引导下鼻气管插管的比较:一项单盲随机前瞻性研究。

Comparison between lignocaine nebulization and airway nerve block for awake fiberoptic bronchoscopy-guided nasotracheal intubation: a single-blind randomized prospective study.

作者信息

Mathur Pooja Rawat, Jain Neena, Kumar Aji, Thada Beena, Mathur Veena, Garg Deepak

机构信息

Department of Anesthesia, Jawaharlal Nehru Medical College, Ajmer, India.

出版信息

Korean J Anesthesiol. 2018 Apr;71(2):120-126. doi: 10.4097/kjae.2018.71.2.120. Epub 2018 Apr 2.

Abstract

BACKGROUND

The preferred management strategy for difficult airways is awake fiberoptic bronchoscopy-guided intubation, which requires effective airway anesthesia to ensure patient comfort and acceptance. This randomized single-blind prospective study was conducted to compare lignocaine nebulization and airway nerve block for airway anesthesia prior to awake fiberoptic bronchoscopy-guided intubation.

METHODS

Sixty adult patients scheduled for surgical procedures under general anesthesia were randomly allocated to two groups. Group N received jet nebulization (10 ml of 4% lignocaine) and Group B received bilateral superior laryngeal and transtracheal recurrent laryngeal nerve blocks (each with 2 ml of 2% lignocaine) followed by fiberoptic bronchoscopy-guided nasotracheal intubation. All patients received procedural sedation with dexmedetomidine. The intubation time, intubating conditions, vocal cord position, cough severity, and degree of patient satisfaction were recorded. Student's test was used to analyze parametric data, while the Mann-Whitney test was applied to non-parametric data and Fisher's test to categorical data. P values < 0.05 were considered statistically significant.

RESULTS

The time taken for intubation was significantly shorter in Group B [115.2 (14.7) s compared with Group N [214.0 (22.2) s] (P = 0.029). The intubating conditions and degree of patient comfort were better in Group B compared with Group N. Although all patients were successfully intubated, patient satisfaction was higher in Group B.

CONCLUSIONS

Airway nerve blocks are preferable to lignocaine nebulization as they provide superior-quality airway anesthesia. However, nebulization may be a suitable alternative when a nerve block is not feasible.

摘要

背景

困难气道的首选管理策略是清醒纤维支气管镜引导插管,这需要有效的气道麻醉以确保患者的舒适度和接受度。本随机单盲前瞻性研究旨在比较清醒纤维支气管镜引导插管前利多卡因雾化和气道神经阻滞用于气道麻醉的效果。

方法

60例计划接受全身麻醉手术的成年患者被随机分为两组。N组接受喷射雾化(10 ml 4%利多卡因),B组接受双侧喉上神经和经气管喉返神经阻滞(各2 ml 2%利多卡因),随后进行纤维支气管镜引导下经鼻气管插管。所有患者均接受右美托咪定进行程序性镇静。记录插管时间、插管条件、声带位置、咳嗽严重程度和患者满意度。采用学生t检验分析参数数据,采用曼-惠特尼U检验分析非参数数据,采用费舍尔检验分析分类数据。P值<0.05被认为具有统计学意义。

结果

B组的插管时间明显短于N组[115.2(14.7)秒比N组[214.0(22.2)秒](P = 0.029)。与N组相比,B组的插管条件和患者舒适度更好。虽然所有患者均成功插管,但B组患者的满意度更高。

结论

气道神经阻滞优于利多卡因雾化,因为它能提供更高质量的气道麻醉。然而,当神经阻滞不可行时,雾化可能是一种合适的替代方法。

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