Mariniello Giuseppe, Corvino Sergio, Corazzelli Giuseppe, Maiuri Francesco
Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, "Federico II" University, Naples, Italy.
Surg Neurol Int. 2023 Mar 24;14:102. doi: 10.25259/SNI_114_2023. eCollection 2023.
The anterior approach to the cervical spine is safe and effective, but not without risks. The pharyngoesophageal perforation (PEP) is a rare but potentially life-threatening complication of this surgical route. A prompt diagnosis and adequate treatment are crucial for the prognosis; nevertheless, there is no unique consent about the best management.
A 47-year-old woman was referred to our neurosurgical unit for clinical and neuroradiological signs of multilevel cervical spine spondylodiscitis, which was conservatively treated with long-term antibiotic therapy and cervical immobilization after computed tomography-guided biopsy. Nine months later, when the infection was resolved, the patient underwent C3-C6 spinal fusion with anterior plate and screws through anterior approach to the cervical spine for degenerative vertebral changes causing severe myelopathy, and C5- C6 retrolisthesis with instability. Five days after surgical procedure, the patient developed a pharyngoesophageal-cutaneous fistula, detected through wound drainage, and confirmed by swallowing contrast study, without systemic signs of infection. The PEP was conservatively treated, with antibiotic therapy and parenteral nutrition, and it was monitored through seriate swallowing contrast and magnetic resonance studies up to the complete resolution.
The PEP is a potentially fatal complication of the anterior cervical spine surgery. We suggest an accurate intraoperative control of the pharyngoesophageal's tract integrity at the end of the surgical procedure and a longtime follow-up, because the risk of occurrence is up to several years after surgery.
颈椎前路手术安全有效,但并非毫无风险。咽食管穿孔(PEP)是该手术路径中一种罕见但可能危及生命的并发症。及时诊断和充分治疗对预后至关重要;然而,对于最佳治疗方法尚无统一共识。
一名47岁女性因多节段颈椎椎体骨髓炎的临床和神经放射学征象被转诊至我们的神经外科病房,在计算机断层扫描引导下活检后,采用长期抗生素治疗和颈椎固定进行保守治疗。九个月后,感染得到解决,患者因退行性椎体改变导致严重脊髓病以及C5 - C6椎体后滑脱伴不稳定,通过颈椎前路进行了C3 - C6椎体融合术,使用前路钢板和螺钉。手术后五天,患者出现咽食管皮肤瘘,通过伤口引流发现,并经吞咽造影检查证实,无全身感染迹象。PEP采用保守治疗,给予抗生素治疗和肠外营养,并通过系列吞咽造影和磁共振检查进行监测,直至完全愈合。
PEP是颈椎前路手术的一种潜在致命并发症。我们建议在手术结束时准确术中控制咽食管通道的完整性,并进行长期随访观察,因为发病风险可持续至术后数年。