Perkkiö J, Keskinen R, Heikkonen J, Mäntylä M
Med Phys. 1986 Mar-Apr;13(2):229-32. doi: 10.1118/1.595901.
Regional blood flow measurements were analyzed using a two-compartment model. The distribution of injected tracer between blood and tissue was assumed to be in equilibrium only at the beginning of the experiment. Equations for the determination of the partition coefficient of injected radionuclides from in vivo measurements were derived. These equations can also be used for estimation of the relative blood content of a tumor or an organ. The results were applied to experiments, where three diffusible radionuclides were injected simultaneously into patients with diagnosed tumors.
使用双室模型分析局部血流测量结果。仅在实验开始时假定注入的示踪剂在血液和组织之间的分布处于平衡状态。推导了根据体内测量确定注入放射性核素分配系数的方程。这些方程也可用于估计肿瘤或器官的相对血容量。将结果应用于实验中，在这些实验中，将三种可扩散放射性核素同时注入已确诊肿瘤的患者体内。
