Huchzermeyer H, Schmitz-Feuerhake I, Reblin T
Eur J Clin Invest. 1977 Oct;7(5):345-9. doi: 10.1111/j.1365-2362.1977.tb01618.x.
We have evaluated the 133Xenon inhalation method for the determination of splenic blood flow. In twenty-two healthy persons the blood flow was on average 109 +/- 4 mg/100 g X min, which is equivalent to a total blood flow of about 170 ml/min. In patients with chronic fatty liver hepatitis specific blood flow was reduced (81 +/- 10 ml/100 g X min) as it was in patients with cirrhotic liver without splenomegaly (75 +/- 2 ml/100 g X min). With increasing weight of the spleen, the total blood flow rises, although specific blood flow is low. Our results obtained by the 133Xenon inhalation method are similar to results obtained by others using intraarterial injection of tracer gas. The advantages of the inhalation method as a non-traumatic method are: (1) the stress for the patient is very small; (2) blood flow measurements can be repeated within short periods of time. We consider for the present the 133Xenon inhalation method to be the method of choice for the determination of the splenic blood flow.
我们评估了用氙-133吸入法测定脾血流量。在22名健康人身上，血流量平均为109±4毫克/100克×分钟，这相当于总血流量约为170毫升/分钟。在慢性脂肪性肝炎患者中，特定血流量降低（81±10毫升/100克×分钟），在无脾肿大的肝硬化患者中也是如此（75±2毫升/100克×分钟）。随着脾脏重量增加，总血流量上升，尽管特定血流量较低。我们通过氙-133吸入法获得的结果与其他人使用动脉内注射示踪气体获得的结果相似。吸入法作为一种非创伤性方法的优点是：（1）对患者的压力非常小；（2）血流量测量可在短时间内重复进行。目前我们认为氙-133吸入法是测定脾血流量的首选方法。
