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瓦尔登斯特伦巨球蛋白血症患者中类似恶性肿瘤的支原体感染。

Mycoplasma infection mimicking a malignancy in a waldenstrom macroglobulinemia patient.

机构信息

Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, China.

Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 310000, China.

出版信息

BMC Infect Dis. 2023 Apr 7;23(1):219. doi: 10.1186/s12879-023-08163-6.

DOI:10.1186/s12879-023-08163-6
PMID:37029352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10080790/
Abstract

BACKGROUND

Mycoplasma hominis infection is common in urinary tract. F-FDG-PET/CT is a valuable tool for tumor and infection diagnosis. Few studies have shown the F-FDG-PET/CT images after mycoplasma infection.

CASE PRESENTATION

Here we described a case of Waldenstrom macroglobulinemia with thickened bladder wall. The F-FDG-PET/CT showed the SUVmax up to 36.1 mimicking bladder cancer. The results of histopathological examination and metagenomic sequencing of the blood and urinary revealed the Mycoplasma hominis infection.

CONCLUSION

The full consideration should be given to the possibility of infection besides tumor in lesions with high SUV value in F-FDG-PET/CT, especially in immunodeficiency patients.

摘要

背景

人型支原体感染在泌尿道很常见。18F-FDG-PET/CT 是肿瘤和感染诊断的一种有价值的工具。很少有研究显示人型支原体感染后的 18F-FDG-PET/CT 图像。

病例介绍

在这里,我们描述了一例伴有膀胱壁增厚的华氏巨球蛋白血症病例。18F-FDG-PET/CT 显示 SUVmax 高达 36.1,类似于膀胱癌。血液和尿液的组织病理学检查和宏基因组测序结果显示为人型支原体感染。

结论

在 18F-FDG-PET/CT 中,对于 SUV 值高的病变,除了肿瘤外,还应充分考虑感染的可能性,特别是在免疫缺陷患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/9d14e14c4ce2/12879_2023_8163_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/5c5c1c00e17c/12879_2023_8163_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/9d14e14c4ce2/12879_2023_8163_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/5c5c1c00e17c/12879_2023_8163_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/9d14e14c4ce2/12879_2023_8163_Fig2_HTML.jpg

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The yield of F FDG PET-CT for the investigation of fever of unknown origin, compared with diagnostic CT.氟代脱氧葡萄糖正电子发射断层扫描-计算机断层扫描(FDG PET-CT)在不明原因发热中的应用与诊断 CT 相比的检出率。
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Tetracycline Resistance Mediated by (M) Has Variable Integrative Conjugative Element Composition in Mycoplasma hominis Strains Isolated in the United Kingdom from 2005 to 2015.2005 年至 2015 年期间,从英国分离的人型支原体菌株中,(M)介导的四环素耐药性具有可变的整合性共轭元件组成。
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