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瓦尔登斯特伦巨球蛋白血症患者中类似恶性肿瘤的支原体感染。

Mycoplasma infection mimicking a malignancy in a waldenstrom macroglobulinemia patient.

机构信息

Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, China.

Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 310000, China.

出版信息

BMC Infect Dis. 2023 Apr 7;23(1):219. doi: 10.1186/s12879-023-08163-6.

Abstract

BACKGROUND

Mycoplasma hominis infection is common in urinary tract. F-FDG-PET/CT is a valuable tool for tumor and infection diagnosis. Few studies have shown the F-FDG-PET/CT images after mycoplasma infection.

CASE PRESENTATION

Here we described a case of Waldenstrom macroglobulinemia with thickened bladder wall. The F-FDG-PET/CT showed the SUVmax up to 36.1 mimicking bladder cancer. The results of histopathological examination and metagenomic sequencing of the blood and urinary revealed the Mycoplasma hominis infection.

CONCLUSION

The full consideration should be given to the possibility of infection besides tumor in lesions with high SUV value in F-FDG-PET/CT, especially in immunodeficiency patients.

摘要

背景

人型支原体感染在泌尿道很常见。18F-FDG-PET/CT 是肿瘤和感染诊断的一种有价值的工具。很少有研究显示人型支原体感染后的 18F-FDG-PET/CT 图像。

病例介绍

在这里,我们描述了一例伴有膀胱壁增厚的华氏巨球蛋白血症病例。18F-FDG-PET/CT 显示 SUVmax 高达 36.1,类似于膀胱癌。血液和尿液的组织病理学检查和宏基因组测序结果显示为人型支原体感染。

结论

在 18F-FDG-PET/CT 中,对于 SUV 值高的病变,除了肿瘤外,还应充分考虑感染的可能性,特别是在免疫缺陷患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6663/10080790/5c5c1c00e17c/12879_2023_8163_Fig1_HTML.jpg

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