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生物可吸收敷料联合抗菌喷雾治疗三度烧伤的疗效。

Efficacy of bioabsorbable dressing combined with antibacterial spray for treatment of third-degree burns.

机构信息

Department of Burn and Plastic Surgery, People's Hospital of Hengshui City, Hebei Province, Hengshui, Hebei, 053000 China.

People's Hospital of Jingxian City, Hebei Province, Jingxian, Hebei, 053500 China.

出版信息

J Wound Care. 2023 Apr 2;32(4):220-228. doi: 10.12968/jowc.2023.32.4.220.

Abstract

OBJECTIVE

To evaluate the clinical efficacy of a bioabsorbable dressing in combination with antibacterial spray in treating third-degree burns.

METHOD

Patients with third-degree burns in our hospital from February 2019 to February 2020 were enrolled and divided into an experimental group and a control group. In all patients, two wound repair surgeries were performed. During the first surgery, bioabsorbable dressing (PELNAC, Gunze Medical Equipment (Shenzhen) Co. Ltd., China) was used for wound treatment. During the second surgery, autologous split-thickness skin graft was performed. For patients in the experimental group, bioabsorbable dressings (PELNAC) were uniformly applied with antibacterial spray during the operation and during postoperative dressing. For patients in the control group, antibacterial spray was not used.

RESULTS

A total of 68 patients took part in the study (experimental group n=36; control group n=32). Infection rate in the experimental group was significantly lower than that in the control group (2.8% versus 21.9%, respectively; p<0.05). The mean wound healing time in the experimental group was shorter by 3.2 days and the wound healing rate of the experimental group was significantly higher than that in the control group (p<0.05). Vancouver Scar Scale (VSS) scores at specific postoperative time intervals were significantly reduced in the experimental group compared with those in the control group (p<0.05).

CONCLUSION

Bioabsorbable dressing combined with antibacterial spray could reduce infection rate, shorten wound healing time and reduce scar formation in repairing third-degree burns.

摘要

目的

评估生物可吸收敷料联合抗菌喷雾在治疗三度烧伤中的临床疗效。

方法

选取我院 2019 年 2 月至 2020 年 2 月收治的三度烧伤患者,分为实验组和对照组。所有患者均进行两次创面修复手术。第一次手术时,使用生物可吸收敷料(PELNAC,珠海健帆生物科技股份有限公司,中国)处理创面。第二次手术时,进行自体刃厚皮片移植。实验组患者在手术过程中和术后换药时,将生物可吸收敷料(PELNAC)均匀喷洒抗菌喷雾。对照组患者则不使用抗菌喷雾。

结果

共有 68 例患者参与研究(实验组 n=36;对照组 n=32)。实验组的感染率明显低于对照组(分别为 2.8%和 21.9%;p<0.05)。实验组的平均愈合时间缩短了 3.2 天,愈合率明显高于对照组(p<0.05)。实验组在特定的术后时间间隔的温哥华瘢痕量表(VSS)评分明显低于对照组(p<0.05)。

结论

生物可吸收敷料联合抗菌喷雾可降低三度烧伤修复后的感染率,缩短愈合时间,减少瘢痕形成。

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