• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

培奈可联合物理抗菌喷雾修复面部丘疹继发性创面的有效性:一项前瞻性随机临床试验

The Effectiveness of PELNAC Combined with Physical Antibacterial Spray in Repairing Secondary Wounds of Facial Bumps: A Pilot Randomized Clinical Trial.

作者信息

Wang Xiangli, Li Yongchao, Liu Ting, Liu Chan, Lv Yeda, Liu Dongxu, Yuan Zhiming

机构信息

Department of Anorectal and Burn Plastic Surgery, People's Hospital of Hengshui City, Hebei Province, Hengshui, 053000, Hebei, China.

Department of Burn and Plastic Surgery, People's Hospital of Hengshui City, Hebei Province, Hengshui, 053000, Hebei, China.

出版信息

Aesthetic Plast Surg. 2025 Apr 30. doi: 10.1007/s00266-025-04882-0.

DOI:10.1007/s00266-025-04882-0
PMID:40307600
Abstract

BACKGROUND

This study aimed to report the clinical effectiveness advantages of absorbable dressing (PELNAC) combined with physical antibacterial spray dressing in repairing secondary wounds from facial bumps.

METHODS

Thirty-two patients comprising 20 in the experimental and 12 in the control group, respectively, were randomly selected. They had undergone excision or extended excision of facial bumps with wounds that could not be directly sutured. In the experimental group, after mass excision, the wounds were covered with PELNAC. In the control group, secondary wounds were repaired by skin grafts or skin flaps after mass excision or extended excision. The postoperative infection rate, healing rate, average healing time, scar formation, and sensory recovery were compared between the two groups.

RESULTS

The wound infection rate in the experimental group was significantly lower than in the control group (P<0.05); the surgery time for the experimental group was shortened by 1.5 h compared to the control group (P<0.05). Four weeks after surgery, all wounds in the experimental group had healed, with a significantly higher healing rate than in the control group (P<0.05). During follow-up, the scar scores in the experimental group were significantly lower than those in the control group (P<0.05).

CONCLUSION

The combination of PELNAC and physical antibacterial spray dressing in the repair of secondary wounds from facial bumps significantly reduced the incidence of wound infection, accelerated wound healing, reduced scar formation at the graft site, and minimized surgical trauma to the donor site.

LEVEL OF EVIDENCE I

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

背景

本研究旨在报告可吸收敷料(聚乳酸羟基乙酸共聚物)联合物理抗菌喷雾敷料修复面部肿块继发创面的临床疗效优势。

方法

随机选取32例患者,其中试验组20例,对照组12例。这些患者均接受了面部肿块切除或扩大切除,创面无法直接缝合。试验组在肿块切除后,创面覆盖聚乳酸羟基乙酸共聚物敷料。对照组在肿块切除或扩大切除后,采用植皮或皮瓣修复继发创面。比较两组术后感染率、愈合率、平均愈合时间、瘢痕形成及感觉恢复情况。

结果

试验组创面感染率显著低于对照组(P<0.05);试验组手术时间较对照组缩短1.5小时(P<0.05)。术后4周,试验组所有创面均愈合,愈合率显著高于对照组(P<0.05)。随访期间,试验组瘢痕评分显著低于对照组(P<0.05)。

结论

聚乳酸羟基乙酸共聚物联合物理抗菌喷雾敷料修复面部肿块继发创面,显著降低了创面感染发生率,加速了创面愈合,减少了植皮部位瘢痕形成,并将供区手术创伤降至最低。

证据水平I:本刊要求作者为每篇文章指定证据水平。有关这些循证医学评级的完整描述,请参阅目录或作者在线指南www.springer.com/00266 。

相似文献

1
The Effectiveness of PELNAC Combined with Physical Antibacterial Spray in Repairing Secondary Wounds of Facial Bumps: A Pilot Randomized Clinical Trial.培奈可联合物理抗菌喷雾修复面部丘疹继发性创面的有效性:一项前瞻性随机临床试验
Aesthetic Plast Surg. 2025 Apr 30. doi: 10.1007/s00266-025-04882-0.
2
Efficacy of bioabsorbable dressing combined with antibacterial spray for treatment of third-degree burns.生物可吸收敷料联合抗菌喷雾治疗三度烧伤的疗效。
J Wound Care. 2023 Apr 2;32(4):220-228. doi: 10.12968/jowc.2023.32.4.220.
3
[Clinical effects of different types of tissue flaps in repairing the wounds with steel plate exposure and infection after proximal tibial fracture surgery].[不同类型组织瓣修复胫骨近端骨折术后钢板外露及感染创面的临床效果]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023 Dec 20;39(12):1140-1148. doi: 10.3760/cma.j.cn501225-20231101-00171.
4
[A prospective randomized controlled study of the application effect of hydrogel dressings on deep partial-thickness burn wounds after dermabrasion and tangential excision].[水凝胶敷料在削痂及削痂联合切痂后深Ⅱ度烧伤创面应用效果的前瞻性随机对照研究]
Zhonghua Shao Shang Za Zhi. 2021 Nov 20;37(11):1085-1089. doi: 10.3760/cma.j.cn501120-20210419-00133.
5
[Clinical effects of free descending branch tissue flap of lateral circumflex femoral artery in repairing Wagner grade 3 or 4 diabetic foot wounds].旋股外侧动脉降支游离组织瓣修复Wagner 3或4级糖尿病足创面的临床疗效
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Dec 20;38(12):1148-1155. doi: 10.3760/cma.j.cn501225-20220321-00076.
6
[Clinical effects of scalp flaps pedicled with superficial temporal artery parietal branch in repairing facial destructive burn wounds].颞浅动脉顶支蒂头皮瓣修复面部深度烧伤创面的临床效果
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023 Oct 20;39(10):919-925. doi: 10.3760/cma.j.cn501225-20230312-00077.
7
Repair of refractory wounds through grafting of artificial dermis and autologous epidermis aided by vacuum-assisted closure.通过负压封闭辅助下的人工真皮与自体表皮移植修复难治性创面。
Aesthetic Plast Surg. 2014 Aug;38(4):727-32. doi: 10.1007/s00266-014-0341-3. Epub 2014 Jun 6.
8
One-step approach for full-thickness skin defect reconstruction in rats using minced split-thickness skin grafts with Pelnac overlay.使用带Pelnac覆盖物的切碎的断层皮片对大鼠全层皮肤缺损进行重建的一步法。
Burns Trauma. 2019 Aug 13;7:19. doi: 10.1186/s41038-019-0157-0. eCollection 2019.
9
[Effects of reactive oxygen species-responsive antibacterial microneedles on the full-thickness skin defect wounds with bacterial colonization in diabetic mice].活性氧响应性抗菌微针治疗糖尿病小鼠全层皮肤缺损伴细菌定植伤口的效果
Zhonghua Shao Shang Za Zhi. 2021 Nov 20;37(11):1024-1035. doi: 10.3760/cma.j.cn501120-20210831-00299.
10
[Effect of autologous skin paste on repairing wound of donor site of medium-thickness skin graft].[自体皮浆对中厚皮片供皮区创面修复的作用]
Zhonghua Shao Shang Za Zhi. 2021 Mar 3;37(3):1-5. doi: 10.3760/cma.j.cn501120-20200304-00121.

本文引用的文献

1
Aesthetician Role in Facial Plastic Surgery and Systemic Therapy for Healthy Skin.美容师在面部整形手术和健康皮肤的全身治疗中的作用。
Facial Plast Surg Clin North Am. 2023 Nov;31(4):557-566. doi: 10.1016/j.fsc.2023.05.007. Epub 2023 Sep 1.
2
Risk Factors for Postsurgical Infections in Facial Feminization Surgery.面部女性化手术术后感染的危险因素。
Aesthetic Plast Surg. 2023 Oct;47(5):2130-2135. doi: 10.1007/s00266-023-03509-6. Epub 2023 Jul 27.
3
Syndactyly release with the use of the Pelnac™ artificial dermal substitute without skin grafting.
应用 Pelnac™人工真皮替代物行并指松解,无需植皮。
J Plast Reconstr Aesthet Surg. 2023 Sep;84:115-120. doi: 10.1016/j.bjps.2023.05.043. Epub 2023 May 22.
4
Efficacy of bioabsorbable dressing combined with antibacterial spray for treatment of third-degree burns.生物可吸收敷料联合抗菌喷雾治疗三度烧伤的疗效。
J Wound Care. 2023 Apr 2;32(4):220-228. doi: 10.12968/jowc.2023.32.4.220.
5
Reducing Risks of Facial Scarring.降低面部瘢痕形成风险。
Facial Plast Surg Clin North Am. 2023 May;31(2):195-207. doi: 10.1016/j.fsc.2023.01.003.
6
Clinical application of absorbable collagen thread and cosmetic suture technique in emergency treatment of children's facial trauma.可吸收胶原线和美容缝合技术在儿童面部创伤急诊治疗中的临床应用。
J Paediatr Child Health. 2022 Nov;58(11):2039-2043. doi: 10.1111/jpc.16147. Epub 2022 Aug 4.
7
Skin grafting.植皮术。
Tidsskr Nor Laegeforen. 2022 May 23;142(8). doi: 10.4045/tidsskr.21.0671. Print 2022 May 24.
8
Evaluation of three methods of suture for skin closure in total knee arthroplasty: a randomized trial.评价三种全膝关节置换术皮肤缝合方法:一项随机试验。
BMC Musculoskelet Disord. 2021 Aug 30;22(1):747. doi: 10.1186/s12891-021-04627-5.
9
Facial Swelling Post-Surgery.术后面部肿胀
J Emerg Med. 2020 Sep;59(3):e93-e94. doi: 10.1016/j.jemermed.2020.06.035. Epub 2020 Jul 22.
10
Appearance-related psychosocial distress following facial skin cancer surgery using the FACE-Q Skin Cancer.面部皮肤癌手术后与容貌相关的心理社会困扰:采用 FACE-Q 皮肤癌量表评估
Arch Dermatol Res. 2019 Nov;311(9):691-696. doi: 10.1007/s00403-019-01957-2. Epub 2019 Jul 23.