School of Nursing, Queensland University of Technology, Victoria Park Rd, Kelvin Grove, QLD 4059.
Centre for Healthcare Transformation, Faculty of Health, Queensland University of Technology.
J Wound Care. 2023 Apr 2;32(4):229-234. doi: 10.12968/jowc.2023.32.4.229.
To internationally validate a tool for predicting the risk of delayed healing of venous leg ulcers (VLUs).
A 10-item tool including sociodemographic factors, venous history, ulcer and lower limb characteristics, compression and mobility items to determine the risk of delayed healing of VLUs has previously been developed and validated in Australia. This study prospectively validated this tool using receiver operating characteristic (ROC) methods; using the area under the curve (AUC) to quantify the discriminatory capability of the tool to analyse the international populations of the UK, Austria and New Zealand.
The validation of the tool in the UK, Austria and New Zealand has indicated that the model has moderate discrimination and goodness-of-fit with an AUC of 0.74 (95% CI: 0.66-0.82) for the total risk assessment score.
The international validation of a risk assessment tool for delayed healing of VLUs will allow clinicians globally to be able to determine realistic outcomes from an early assessment and to be able to guide early tailored interventions to address the specific modifiable risk factors and thus promote timely healing.
对一种用于预测静脉下肢溃疡（VLU）愈合延迟风险的工具进行国际验证。
先前已在澳大利亚开发并验证了一种包含社会人口统计学因素、静脉病史、溃疡和下肢特征、压迫和活动度项目的 10 项工具，以确定 VLU 愈合延迟的风险。本研究使用接收者操作特征（ROC）方法前瞻性地验证了该工具；使用曲线下面积（AUC）来量化工具的区分能力，以分析英国、奥地利和新西兰的国际人群。
该工具在英国、奥地利和新西兰的验证表明，该模型具有中度的区分度和拟合优度，总风险评估评分的 AUC 为 0.74（95%CI：0.66-0.82）。
对 VLU 愈合延迟风险评估工具的国际验证将使全球的临床医生能够从早期评估中确定现实的结果，并能够指导早期的针对性干预，以解决特定的可改变的风险因素，从而促进及时愈合。
