Cardiothoracic Department, Freeman Hospital, Newcastle-Upon-Tyne, NE7 7DN, United Kingdom.
J Invasive Cardiol. 2023 Apr;35:E169-E178. doi: 10.25270/jic/22.00342.
Myocardial muscle bridging is not uncommon; it is usually asymptomatic and on occasion can be associated with angina or even acute coronary syndrome. Traditionally, percutaneous intervention is not advocated and medical management or cardiac surgery, with unroofing of the bridge, is advised if troublesome symptoms occur.
To describe the experience and outcome of percutaneous intervention and stenting of symptomatic myocardial muscle bridges.
A retrospective analysis of prospectively collected data on all patients with symptomatic muscle bridge who were treated with stent insertion after physiologic and intravascular ultrasound assessment was performed. Follow-up of all patients up to 7 years was documented and repeat angiography was performed in 4 of these patients.
Seven patients were identified with muscle bridge who were symptomatic and were managed with maximum medical therapy but remained symptomatic. They all underwent percutaneous procedure with physiologic assessment of the muscle bridge with fractional flow reserve and with intravascular ultrasound, which was also used to optimize the stent procedure. All patients remain well and asymptomatic with follow-up from 2-7 years. Two patients had atypical symptoms and had repeat angiography at 18 and 28 months, respectively, and 2 more patients had a follow-up angiography at 32 and 34 months; all showed patent stents and no evidence of any issues.
Percutaneous intervention and stent for symptomatic muscle bridges performed with physiological and intracoronary imaging assessment and guidance may be an acceptable management modality for symptomatic MB patients, resulting in a good outcome and potentially sparing patients a highly invasive cardiac surgery.
心肌肌桥并不少见;通常无症状,但有时可与心绞痛甚至急性冠脉综合征相关。传统上不提倡经皮介入治疗,如果出现麻烦的症状,建议进行药物治疗或心脏手术,行桥血管切开术。
描述经皮介入治疗和支架置入治疗有症状心肌肌桥的经验和结果。
对所有经生理和血管内超声评估后,因症状性肌桥而行支架置入的患者进行前瞻性收集数据的回顾性分析。记录所有患者的 7 年随访情况,并对其中 4 例患者进行重复血管造影。
确定了 7 例有症状的肌桥患者,他们接受了最大药物治疗但仍有症状。所有患者均接受了经皮介入治疗,包括心肌桥的生理评估(使用血流储备分数)和血管内超声检查,还用于优化支架手术。所有患者均无症状,随访 2 至 7 年。2 例患者有非典型症状,分别在 18 个月和 28 个月时进行了重复血管造影,另外 2 例患者在 32 个月和 34 个月时进行了随访血管造影;所有患者均显示支架通畅,无任何问题。
对有症状的肌桥患者进行经皮介入治疗和支架置入,结合生理和冠状动脉内成像评估和指导,可能是一种可接受的治疗方法,可获得良好的结果,并可能使患者避免高度侵袭性的心脏手术。