制备了杀虫剂浸渍的聚酯/棉混纺织物，并评估了其对臭虫和登革热传播媒介白纹伊蚊和埃及伊蚊的驱避特性。

Development of insecticide-impregnated polyester/cotton blend fabric and assessment of their repellent characteristics against Cimex lectularius and dengue vectors Aedes albopictus and Aedes aegypti.

机构信息

Division of Pharmaceutical Technology, Defence Research Laboratory (DRL), DRDO, Tezpur, 784001, Assam, India.

出版信息

Parasit Vectors. 2023 Apr 9;16(1):122. doi: 10.1186/s13071-023-05740-1.

DOI:10.1186/s13071-023-05740-1

PMID:37032336

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10082990/

Abstract

BACKGROUND

Personal protection measures using insecticide-treated fabric is one of the most effective strategies to prevent the bites of hematophagous insects. Many countries have had success treating fabrics with pyrethroids on an individual level.

METHODS

In the current study, a new combination of insecticides, alpha-cypermethrin (ACP) and deltamethrin (DET), has been impregnated on fabric composed of a 50:50 blend of polyester and cotton. Residual and morphological analysis was performed along with the evaluation of physical parameters. Biological evaluations were performed to check the repellency, knockdown, and mortality of insecticide-impregnated fabric (IIF) against bed bugs (Cimex lectularius) using Petri plate assay and mosquitoes (Aedes aegypti and Aedes albopictus) using cone bioassay.

RESULTS

The results showed the repellency of IIF to be 56.6% for C. lectularius and a knockdown percentage of 53.3% and 63.3% for Ae. aegypti and Ae. albopictus, respectively. A > 80% mortality was found for both species of mosquitoes up to 20 cycles of washing with no significant difference (P > 0.05). From high-performance liquid chromatography (HPLC) analysis, the reduction in the contents of ACP and DET after subsequent washes can be correlated with the overall decrease in bioefficacy. ACP and DET remaining in unit gram of fabric after 20 wash cycles were found to be 5.4 mg and 3.1 mg, respectively. By examining the fabric's surface morphology using scanning electron microscope (SEM) and utilizing energy-dispersive x-ray (EDX) analysis, it was possible to identify the presence of insecticides that were adhered to the fabric. Differential scanning calorimetry (DSC) showed distinctive endothermic peak of insecticide at 98.3 ºC, whereas no change in thermal behavior was observed from thermo-gravimetric analysis (TGA). Furthermore, the physical attributes of IIF provide conclusive evidence for its firmness.

CONCLUSION

All experimental findings were consistent with the potential use of IIF as a bed bug- and mosquito-repellent fabric to be used against hematophagous infestations. This fabric can serve as a potential strategy to control vector-borne diseases like dengue, malaria, trench fever, etc.

摘要

背景

使用杀虫剂处理过的织物进行个人防护是预防吸血昆虫叮咬的最有效策略之一。许多国家都成功地对个人使用拟除虫菊酯处理过织物。

方法

在目前的研究中，一种新型杀虫剂α氯氰菊酯（ACP）和氯菊酯（DET）的组合已被浸渍在由聚酯和棉各占 50%的混合织物上。进行了残留和形态分析，以及物理参数的评估。使用培养皿测定法评估了防虫织物（IIF）对床虱（Cimex lectularius）的驱避性、击倒性和死亡率，以及使用锥形生物测定法评估了对蚊子（埃及伊蚊和白纹伊蚊）的驱避性、击倒性和死亡率。

结果

结果表明，IIF 对 C. lectularius 的驱避率为 56.6%，对埃及伊蚊和白纹伊蚊的击倒率分别为 53.3%和 63.3%。两种蚊子在 20 次洗涤循环中均达到 >80%的死亡率，且无显著差异（P>0.05）。高效液相色谱（HPLC）分析表明，随着洗涤次数的增加，ACP 和 DET 的含量减少，生物功效总体下降。在 20 次洗涤循环后，单位克织物中残留的 ACP 和 DET 分别为 5.4 毫克和 3.1 毫克。通过扫描电子显微镜（SEM）检查织物表面形态，并利用能量色散 X 射线（EDX）分析，发现杀虫剂附着在织物上。差示扫描量热法（DSC）显示杀虫剂在 98.3°C 处有明显的吸热峰，而热重分析（TGA）未观察到热行为的变化。此外，IIF 的物理特性为其坚固性提供了确凿的证据。