Zhang Xuejiao, Yue Zhiling, Yang Sujun
Division of Radiological Imaging Medicine, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Department of Radiology, Handan Central Hospital, Handan, Hebei 056008, P.R. China.
Oncol Lett. 2023 Mar 20;25(5):181. doi: 10.3892/ol.2023.13767. eCollection 2023 May.
Alveolar rhabdomyosarcoma (ARMS) is more common in children and rare in adults. A small number of cases in the stomach of an adult have been documented. The present study describes a case of primary gastric ARMS in a 20-year-old healthy female. The patient was admitted to Handan Central Hospital (Handan, China) with intermittent abdominal pain for >1 month, which was noticeable and progressively worsened after meals, with black stools. Gastroscopy revealed a 2.5-cm ulcer on the side of the greater curvature of the gastric body, and a pathological biopsy revealed a neuroendocrine neoplasm. An enhanced abdominal computed tomography (CT) scan indicated a thickening and an ulcerated mass measuring ~4.5×2.0 cm at the gastric body, with the tumor showing poor enhancement. Finally, a laparoscopic distal gastrectomy was performed. The postoperative pathology combined with immunohistochemical staining indicated that the patient had primary alveolar RMS of the stomach. The present case suggests that an early diagnosis of gastric adenoid RMS is extremely difficult. However, this disease must be investigated in any young person who presents with a gastric mass. The current study presents a rare case of primary ARMS occurring in the stomach; however, more research on this disease is necessary to improve the clinical diagnosis and treatment.
肺泡状横纹肌肉瘤(ARMS)在儿童中更为常见,在成人中罕见。已有少数成人胃内病例的报道。本研究描述了一例20岁健康女性原发性胃ARMS病例。该患者因间歇性腹痛1个多月入住邯郸市中心医院(中国邯郸),腹痛明显,饭后逐渐加重,并伴有黑便。胃镜检查显示胃体大弯侧有一个2.5厘米的溃疡,病理活检显示为神经内分泌肿瘤。腹部增强计算机断层扫描(CT)显示胃体处有一个增厚且溃疡的肿块,大小约为4.5×2.0厘米,肿瘤强化不佳。最后,进行了腹腔镜远端胃切除术。术后病理结合免疫组化染色表明该患者患有原发性胃肺泡状横纹肌肉瘤。本病例表明胃腺样横纹肌肉瘤的早期诊断极其困难。然而,对于任何出现胃肿块的年轻人都必须对这种疾病进行调查。本研究报道了一例罕见的原发性胃ARMS病例;然而,有必要对这种疾病进行更多研究以改善临床诊断和治疗。