Colombo E, Bocchi M, Redaelli D, Spinelli M
Minerva Med. 1986 Mar 17;77(11):387-90.
An endoscopic series of 4610 patients examined for dyspeptic symptoms has been reviewed. The purpose was to verify the prevalence of gastric stump cancer. In 266 patients previously gastrectomized for benign peptic ulcer, 10 cases of gastric carcinoma were found (3.61%) whereas in 4344 not previously gastrectomized patients 157 gastric carcinomas were diagnosed (3.75%). Among the 10 patients affected from gastric stump carcinoma, 5 had been operated before, and 5 after, the age 45. The statistical comparison between the two groups showed a significant difference (p less than 0.02) as for the mean time intervals between surgical intervention and onset of gastric stump carcinoma, whereas the mean ages of onset of gastric stump carcinoma resulted substantially identical. We conclude that advanced age, rather than a previous gastrectomy, confers a major risk of gastric carcinoma.
对4610例因消化不良症状接受内镜检查的患者进行了回顾性研究。目的是核实残胃癌的患病率。在266例先前因良性消化性溃疡接受胃切除术的患者中,发现10例胃癌(3.61%),而在4344例先前未接受胃切除术的患者中,诊断出157例胃癌(3.75%)。在10例残胃癌患者中,5例在45岁之前接受手术,5例在45岁之后接受手术。两组之间的统计比较显示,手术干预与残胃癌发病之间的平均时间间隔存在显著差异(p<0.02),而残胃癌发病的平均年龄基本相同。我们得出结论,高龄而非先前的胃切除术是胃癌的主要危险因素。