• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

气管孤立性纤维瘤的内镜治疗:一例报告

Endoscopic treatment of solitary fibrous tumor of the trachea: a case report.

作者信息

Messina Gaetana, Bove Mary, Natale Giovanni, Fiorelli Alfonso, Vicidomini Giovanni, Santini Mario, Ronchi Andrea, Pirozzi Mario, Facchini Sergio, Ciardiello Fortunato, Fasano Morena

机构信息

Thoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.

Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

出版信息

Transl Cancer Res. 2023 Mar 31;12(3):646-650. doi: 10.21037/tcr-22-1622. Epub 2023 Mar 15.

DOI:10.21037/tcr-22-1622
PMID:37033342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10080464/
Abstract

BACKGROUND

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, generally arising in the visceral pleura. It rarely originates from other sites such as trachea, orbital cavities, nasal cavities, peritoneum, paranasal sinuses, meninges, salivary glands, thyroid gland, diaphragm, liver, pancreas, lung kidney, adrenal gland, mediastinum, spermatid cord, pericardium, urinary bladder, prostate, uterine cervix, testis, spinal cord, periosteum, skin, soft tissue and bone.

CASE DESCRIPTION

We present a surgical case of a rare primary tracheal tumor. High resolution computed tomography (HRCT) scan of the chest showed a 5 mm hypodense lesion, located on the right lateral wall of the proximal third of trachea; however the tracheal lumen was normal. We performed a rigid bronchoscopy in order to remove the endotracheal tumor with palliative purposes only. For this reason, we did not perform a prior histologic examination. The lesion was easily removed with common biopsy forceps and with standard aspirator. The debulking of the tumor was achieved with the use of laser Nd-YAP, electrocautery was used also for hemostasis to prevent bleeding during the operation. Without complications during the endoscopic treatment, the procedure was well tolerated by the patient. The pathological diagnosis was SFT.

CONCLUSIONS

SFT located in the trachea can be endoscopically resceted. Endoscolical treatment is indicated for patients with poor clinical conditions (heart disease, respiratory failure) that are not elegible for surgical resection.

摘要

背景

孤立性纤维瘤(SFT)是一种罕见的间叶性肿瘤,通常起源于脏层胸膜。它很少起源于其他部位,如气管、眼眶、鼻腔、腹膜、鼻窦、脑膜、唾液腺、甲状腺、膈肌、肝脏、胰腺、肺、肾、肾上腺、纵隔、精索、心包、膀胱、前列腺、子宫颈、睾丸、脊髓、骨膜、皮肤、软组织和骨骼。

病例描述

我们报告一例罕见的原发性气管肿瘤的手术病例。胸部高分辨率计算机断层扫描(HRCT)显示在气管近端三分之一右侧壁有一个5毫米的低密度病变;然而气管腔正常。我们仅出于姑息目的进行了硬质支气管镜检查以切除气管内肿瘤。因此,我们未进行术前组织学检查。该病变用普通活检钳和标准吸引器很容易切除。使用钕钇铝石榴石激光(Nd-YAP)实现肿瘤减容,还使用电灼止血以防止手术期间出血。内镜治疗期间无并发症,患者对该手术耐受性良好。病理诊断为SFT。

结论

位于气管的SFT可通过内镜切除。对于不适合手术切除的临床状况较差(心脏病、呼吸衰竭)的患者,建议采用内镜治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/26ac84a6ed8b/tcr-12-03-646-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/156f0203ec01/tcr-12-03-646-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/2ec53f136833/tcr-12-03-646-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/26ac84a6ed8b/tcr-12-03-646-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/156f0203ec01/tcr-12-03-646-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/2ec53f136833/tcr-12-03-646-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f673/10080464/26ac84a6ed8b/tcr-12-03-646-f3.jpg

相似文献

1
Endoscopic treatment of solitary fibrous tumor of the trachea: a case report.气管孤立性纤维瘤的内镜治疗:一例报告
Transl Cancer Res. 2023 Mar 31;12(3):646-650. doi: 10.21037/tcr-22-1622. Epub 2023 Mar 15.
2
Endonasal endoscopic resection of an ethmoidal solitary fibrous tumor.鼻内镜下筛窦孤立性纤维瘤切除术
Eur Arch Otorhinolaryngol. 2006 Sep;263(9):833-7. doi: 10.1007/s00405-006-0073-3. Epub 2006 Jun 9.
3
[Solitary fibrous tumor of the nasopharynx. Apropos of a case].[鼻咽部孤立性纤维瘤。附1例报告]
Ann Otolaryngol Chir Cervicofac. 1997;114(3):71-5.
4
[Solitary Fibrous Tumors of the Nasal and Paranasal Sinuses].[鼻腔及鼻窦孤立性纤维性肿瘤]
Nihon Jibiinkoka Gakkai Kaiho. 2015 Jul;118(7):875-81. doi: 10.3950/jibiinkoka.118.875.
5
An unusual location of solitary fibrous tumor in heart-A case report and review of literature.心脏孤立性纤维瘤的罕见部位——病例报告及文献复习。
Cancer Rep (Hoboken). 2022 Nov;5(11):e1698. doi: 10.1002/cnr2.1698. Epub 2022 Aug 30.
6
Solitary fibrous tumor of the pancreas: Case report and review of the literature.胰腺孤立性纤维瘤:病例报告及文献复习
World J Gastrointest Surg. 2016 Jun 27;8(6):461-6. doi: 10.4240/wjgs.v8.i6.461.
7
Intracranial malignant solitary fibrous tumor metastasized to the chest wall: A case report and review of literature.颅内恶性孤立性纤维瘤转移至胸壁:一例报告并文献复习
World J Clin Cases. 2020 Oct 26;8(20):4844-4852. doi: 10.12998/wjcc.v8.i20.4844.
8
Orbital Solitary Fibrous Tumor眼眶孤立性纤维性肿瘤
9
Two case reports of rare diseases occurring in rare parts: splenic vein solitary fibrous tumor and liver solitary fibrous tumor.罕见部位发生的罕见疾病两例报告:脾静脉孤立性纤维瘤和肝孤立性纤维瘤。
AME Case Rep. 2021 Apr 25;5:17. doi: 10.21037/acr-20-142. eCollection 2021.
10
More advantages in detecting bone and soft tissue metastases from prostate cancer using F-PSMA PET/CT.使用F-PSMA PET/CT检测前列腺癌骨和软组织转移方面有更多优势。
Hell J Nucl Med. 2019 Jan-Apr;22(1):6-9. doi: 10.1967/s002449910952. Epub 2019 Mar 7.

本文引用的文献

1
Noninvasive positive pressure ventilation in the assessment of extrinsic tracheal stenosis.无创正压通气在评估外源性气管狭窄中的应用。
Interact Cardiovasc Thorac Surg. 2022 Jun 15;35(1). doi: 10.1093/icvts/ivac044.
2
Mesenchymal neoplasms: Is it time for cytology? New perspectives for the pre-operative diagnosis of soft tissue tumors in the molecular era.间叶性肿瘤:细胞学诊断的时代是否已经到来?分子时代软组织肿瘤术前诊断的新视角。
Pathol Res Pract. 2020 Jun;216(6):152923. doi: 10.1016/j.prp.2020.152923. Epub 2020 Mar 25.
3
Solitary fibrous tumor of the trachea: a case report.
气管孤立性纤维瘤:一例报告。
Gen Thorac Cardiovasc Surg. 2020 Dec;68(12):1523-1527. doi: 10.1007/s11748-019-01274-5. Epub 2019 Dec 17.
4
Flow-Volume Curve Analysis for Predicting Recurrence After Endoscopic Dilation of Airway Stenosis.气道狭窄内镜扩张后复发的预测:流量-容积曲线分析。
Ann Thorac Surg. 2019 Jul;108(1):203-210. doi: 10.1016/j.athoracsur.2019.01.075. Epub 2019 Mar 12.
5
Extrapleural solitary fibrous tumor: A distinct entity from pleural solitary fibrous tumor. An update on clinical, molecular and diagnostic features.胸膜外孤立性纤维瘤:一种与胸膜孤立性纤维瘤不同的实体。临床、分子及诊断特征的最新进展
Ann Diagn Pathol. 2018 Jun;34:142-150. doi: 10.1016/j.anndiagpath.2018.01.004. Epub 2018 Apr 9.
6
Endobronchial solitary fibrous tumor.支气管内孤立性纤维瘤
Autops Case Rep. 2016 Dec 30;6(4):35-40. doi: 10.4322/acr.2016.053. eCollection 2016 Oct-Dec.
7
[Solitary fibrous tumor in trachea: report of a case].[气管孤立性纤维瘤:1例报告]
Zhonghua Bing Li Xue Za Zhi. 2016 Oct 8;45(10):723-724. doi: 10.3760/cma.j.issn.0529-5807.2016.10.015.
8
ALDH1 is an immunohistochemical diagnostic marker for solitary fibrous tumours and haemangiopericytomas of the meninges emerging from gene profiling study.ALDH1 是免疫组化诊断标志物,用于源自基因谱研究的脑膜孤立性纤维肿瘤和血管外皮细胞瘤。
Acta Neuropathol Commun. 2013 May 9;1:10. doi: 10.1186/2051-5960-1-10.
9
Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor.全面的遗传学分析鉴定出孤立性纤维性肿瘤中具有诊断意义的 NAB2/STAT6 融合基因、非随机的二级基因组不平衡和特征性的基因表达谱。
Genes Chromosomes Cancer. 2013 Oct;52(10):873-86. doi: 10.1002/gcc.22083. Epub 2013 Jun 12.
10
Solitary fibrous tumor: is there a molecular relationship with cellular angiofibroma, spindle cell lipoma, and mammary-type myofibroblastoma?孤立性纤维性肿瘤:与细胞血管纤维瘤、梭形细胞脂肪瘤和乳腺型肌纤维母细胞瘤是否存在分子关系?
Am J Clin Pathol. 2012 Jun;137(6):963-70. doi: 10.1309/AJCPQEG6YNN6CNAL.