Eckert Mark A
bioRxiv. 2023 Mar 30:2023.03.29.534799. doi: 10.1101/2023.03.29.534799.
Heschl's gyrus (HG) can occur as a single gyrus or with a completely duplicated posterior HG that has been related to a variety of abilities and disorders. Voxel-based studies typically involve the normalization of these qualitatively different HG types, thus making it difficult to evaluate the contribution of sulcal/gyral variability to voxel-based effects and perhaps obscuring some effects. To examine the structural covariance of single and duplicated HG, templates were created for the left single and duplicated HG. Structural covariance analysis with a Jacobian measure of volumetric displacement demonstrated consistent spatial covariance with homologous structure in the right hemisphere across qualitatively different HG morphology. These results suggest that HG duplication is aptly named with respect to cortical structure variation and demonstrate a multi-template approach for studying qualitatively unique brain function and structure linked to perceptual and cognitive functions.
Qualitatively unique sulcal/gyral features can affect voxel-based analyses.Heschl's gyrus is highly variable across people.Morphology-specific templates were created to study Heschl's gyrus structural covariance.Single and duplicated Heschl's gyrus exhibited a similar pattern of covariance.
颞横回（HG）可表现为单一脑回，也可伴有完全重复的后HG，这与多种能力和疾病有关。基于体素的研究通常涉及对这些在性质上不同的HG类型进行标准化，因此难以评估脑沟/脑回变异性对基于体素的效应的贡献，并且可能会掩盖一些效应。为了研究单一HG和重复HG的结构协方差，创建了左侧单一HG和重复HG的模板。使用体积位移的雅可比测量进行结构协方差分析表明，在性质上不同的HG形态中，与右半球的同源结构存在一致的空间协方差。这些结果表明，就皮质结构变异而言，HG重复这一命名是恰当的，并展示了一种多模板方法，用于研究与感知和认知功能相关的性质独特的脑功能和结构。
性质独特的脑沟/脑回特征会影响基于体素的分析。颞横回在个体间差异很大。创建了形态特异性模板来研究颞横回的结构协方差。单一HG和重复HG表现出相似的协方差模式。
