Rapoza P A, Quinn T C, Kiessling L A, Taylor H R
Ophthalmology. 1986 Apr;93(4):456-61. doi: 10.1016/s0161-6420(86)33716-3.
Chlamydial conjunctivitis was diagnosed in 46 of 100 infants less than two months old presenting with conjunctivitis. Streptococcus, Staphylococcus, and Hemophilus species were most frequently identified in the remainder. All infants with chlamydial conjunctivitis were black and were born by vaginal delivery (P less than 0.001). Average age at presentation was 13 days for chlamydial and 21 days for other causes of bacterial conjunctivitis (P less than 0.001) with symptoms present an average of five to six days prior to presentation. There was no statistically significant difference in sex, birthweight, APGAR scores, bilaterality, fever, or prophylactic drops administered. Mothers of infants with chlamydial conjunctivitis averaged 19.5 years old versus 23.0 for the bacterial group (P less than 0.001). There was no statistically significant difference in past obstetrical or sexually transmitted disease history. Persistent chlamydial conjunctivitis following a two-week course of oral erythromycin as recommended by Centers for Disease Control was documented in 19% of patients with chlamydial infection.
在100名患有结膜炎的两个月龄以下婴儿中，46名被诊断为衣原体性结膜炎。其余婴儿中最常鉴定出的是链球菌、葡萄球菌和嗜血杆菌属。所有衣原体性结膜炎婴儿均为黑人，通过阴道分娩出生（P<0.001）。衣原体性结膜炎婴儿的平均就诊年龄为13天，其他细菌性结膜炎病因的婴儿为21天（P<0.001），症状出现在就诊前平均五到六天。在性别、出生体重、阿氏评分、双侧性、发热或预防性滴眼液使用方面，没有统计学上的显著差异。衣原体性结膜炎婴儿的母亲平均年龄为19.5岁，而细菌性结膜炎组为23.0岁（P<0.001）。既往产科或性传播疾病史没有统计学上的显著差异。按照疾病控制中心的建议，在接受为期两周的口服红霉素治疗后，19%的衣原体感染患者出现持续性衣原体性结膜炎。
