Sandström I
Acta Paediatr Scand. 1987 Mar;76(2):221-7. doi: 10.1111/j.1651-2227.1987.tb10451.x.
Chlamydia trachomatis was isolated from the most inflamed eye of 13 of 107 (12%) infants with neonatal purulent conjunctivitis and from none of 100 healthy infants (p less than 0.01). Staphylococcus aureus was recovered from 49 (46%) inflamed eyes and from 8 (8%) healthy eyes (p less than 0.01). Streptococcus pneumoniae, Haemophilus influenzae, Branhamella catarrhalis, Escherichia coli and Klebsiella pneumoniae were isolated from very few infants with conjunctivitis but not from controls. No organisms could be recovered from 23 (22%) infants with conjunctivitis and from 60 (60%) healthy infants (p less than 0.01). The incidence of neonatal purulent conjunctivitis was 107 (2%), of 5,924 births. Eyes infected with C. trachomatis were significantly more inflamed than eyes from which S. aureus or no organisms could be isolated. Furthermore, conjunctival "pseudomembranes" were associated with C. trachomatis. The age at onset of the chlamydial conjunctivitis was higher compared to the age at onset of conjunctivitis in which S. aureus or no organisms were isolated.
在107例患有新生儿脓性结膜炎的婴儿中，13例（12%）病情最严重的眼睛分离出沙眼衣原体，而100例健康婴儿的眼睛均未分离出该病原体（p<0.01）。49例（46%）病情严重的眼睛分离出金黄色葡萄球菌，8例（8%）健康婴儿的眼睛也分离出该病原体（p<0.01）。肺炎链球菌、流感嗜血杆菌、卡他莫拉菌、大肠杆菌和肺炎克雷伯菌仅从极少数患有结膜炎的婴儿眼中分离出，对照组未分离出。23例（22%）患有结膜炎的婴儿和60例（60%）健康婴儿的眼睛未分离出任何病原体（p<0.01）。在5924例出生婴儿中，新生儿脓性结膜炎的发病率为107例（2%）。感染沙眼衣原体的眼睛比未分离出金黄色葡萄球菌或任何病原体的眼睛炎症明显更严重。此外，结膜“假膜”与沙眼衣原体有关。与未分离出金黄色葡萄球菌或任何病原体的结膜炎相比，衣原体性结膜炎的发病年龄更高。
