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芬太尼、艾替唑仑及其他:一项社区合作的可行性研究,利用手持式拉曼光谱法识别当地非法毒品供应中的物质。

Fentanyl, etizolam, and beyond: A feasibility study of a community partnership using handheld Raman spectrometry to identify substances in the local illicit drug supply.

作者信息

Grover Casey, How Justine, Close Reb

机构信息

Community Hospital of the Monterey Peninsula, Monterey, CA, USA.

出版信息

J Public Health Res. 2023 Apr 2;12(2):22799036231166313. doi: 10.1177/22799036231166313. eCollection 2023 Apr.

Abstract

BACKGROUND

The United States is currently experiencing an unprecedented rise in fatal drug overdoses, which is in part due to the arrival of fentanyl, fentanyl analogs, and other synthetic drugs into the illicit drug supply. Traditional urine drug testing is often unable to detect fentanyl analogs and other novel synthetic drugs, which places physicians and first responders in the difficult position of treating patients who are intoxicated with or overdosing on unknown substances.

DESIGN AND METHODS

We report, as a feasibility study, the development of a novel program to use a handheld Raman spectrometry device in our hospital's Emergency Department to surveil our local illicit drug supply in terms of what substances are being sold and used.

RESULTS

Using our novel program, we were able to detect 27 substances in our illicit drug supply over a 10 month period, including fentanyl analogues. We shared, through our local opioid safety coalition, real-time information to first responders, substance use treatment programs, and physicians about the novel substances we detected using the handheld Raman spectrometer.

CONCLUSIONS

A community partnership of using handheld Raman spectrometry in our hospital's Emergency Department was successful in providing information to health care providers about novel substances in our illicit drug market. Additionally, the implementation of this program improved collaboration between local health care providers and local law enforcement.

摘要

背景

美国目前正经历致命药物过量使用情况前所未有的上升,部分原因是芬太尼、芬太尼类似物及其他合成药物进入了非法药物供应渠道。传统的尿液药物检测往往无法检测出芬太尼类似物及其他新型合成药物,这使医生和急救人员在治疗因未知物质中毒或过量用药的患者时陷入困境。

设计与方法

作为一项可行性研究,我们报告了一个新项目的开展情况,该项目在我院急诊科使用手持式拉曼光谱仪,以监测本地非法药物供应中正在销售和使用的物质。

结果

通过我们的新项目,在10个月的时间里,我们能够检测出非法药物供应中的27种物质,包括芬太尼类似物。我们通过当地的阿片类药物安全联盟,向急救人员、物质使用治疗项目及医生实时分享了我们使用手持式拉曼光谱仪检测到的新型物质的信息。

结论

我院急诊科开展的利用手持式拉曼光谱仪的社区合作项目成功地向医疗服务提供者提供了有关非法药物市场中新型物质的信息。此外,该项目的实施改善了当地医疗服务提供者与当地执法部门之间的合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0b5/10074623/a350ee8b4922/10.1177_22799036231166313-fig1.jpg

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