Sadykhov I A, Akhmedov R M, Khanbekova E M
Parazitologiia. 1986 Jan-Feb;20(1):74-8.
The biological activity of a new organic compound beta-diethylaminoisobuthironitrile was determined. A new phenomenon for nematodes of open-type larval development (Strongyloid) was found. Alive females of nematodes belonging to the genera Trichostrongylus, Ostertagia, Bunostomum and Haemonchus were treated with 5 volumes-% mixture of the compound with water. The development of eggs of these nematodes in the mother body and output of larvae in female were observed. The larvae lead an active mode of life, feed and are capable of developing. Optimal exposure of females in solution is 4 hours for Haemonchus and Trichostrongylus, 2 hours for Bunostomum, and 3 hours for Ostertagia. Stimulation of egg development in nematodes of semiclose and semi-open types was not observed.
测定了一种新型有机化合物β-二乙氨基异丁腈的生物活性。发现了开放型幼虫发育线虫（类圆线虫）的一种新现象。用该化合物与水的5体积-%混合物处理属于毛圆线虫属、奥斯特他线虫属、牛仰口线虫属和血矛线虫属的线虫活雌虫。观察了这些线虫卵在母体内的发育情况以及雌虫体内幼虫的产出情况。幼虫过着活跃的生活方式，进食并能够发育。对于血矛线虫和毛圆线虫，雌虫在溶液中的最佳暴露时间为4小时，牛仰口线虫为2小时，奥斯特他线虫为3小时。未观察到对半封闭和半开放型线虫卵发育的刺激作用。
