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三对半规管阻塞与迷路切除术治疗梅尼埃病的回顾性研究。

Triple Semicircular Canal Plugging versus Labyrinthectomy for Meniere Disease: A Retrospective Study.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, 250022, China.

出版信息

Laryngoscope. 2023 Nov;133(11):3178-3184. doi: 10.1002/lary.30690. Epub 2023 Apr 10.

Abstract

OBJECTIVES

The study goals were to compare the long-term efficacy of semicircular canal plugging (SCP) with labyrinthectomy in the treatment of advanced Meniere's disease (MD).

STUDY DESIGN

A retrospective study.

SETTING

Single tertiary medical center.

METHODS

A total of 116 MD patients (TSCP group of 90; labyrinthectomy group of 26) with complete medical documents in Shandong Provincial ENT Hospital, from March 2017 to March 2019 were retrospectively analyzed, including a battery of auditory and vestibular function tests, recovery time from imbalance and function level scores (FLS).

RESULTS

The total control rate of vertigo in the TSCP group was 96.7% (87/90). The rate of hearing loss was 23.3% (21/90). The control rate of vertigo in the labyrinthectomy group was 100% (26/26). All patients lost their auditory function after labyrinthectomy with a 100% hearing loss rate. There was no significant difference in the vertigo control rate between the two groups (P > 0.05). The hearing loss rate in the TSCP group was significantly lower than that in the labyrinthectomy group (P < 0.00). The median time recovered from imbalance was 15 days in TSCP group and 21 days in labyrinthectomy group, which is significantly different (P < 0.05). There was no significant difference in the FLS between the two groups (P > 0.05).

CONCLUSIONS

Compared to labyrinthectomy, TSCP can preserve hearing at a high probability; meanwhile, otolith organ function preservation benefits patients from faster vestibular compensation.

LEVEL OF EVIDENCE

3 Laryngoscope, 133:3178-3184, 2023.

摘要

目的

本研究旨在比较半规管阻塞(SCP)与迷路切除术治疗晚期梅尼埃病(MD)的长期疗效。

研究设计

回顾性研究。

设置

单中心三级医疗中心。

方法

回顾性分析 2017 年 3 月至 2019 年 3 月在山东省耳鼻喉医院就诊的 116 例 MD 患者(TSCP 组 90 例;迷路切除术组 26 例)的完整病历资料,包括一系列听觉和前庭功能检查、平衡恢复时间和功能水平评分(FLS)。

结果

TSCP 组眩晕总控制率为 96.7%(87/90),听力损失率为 23.3%(21/90);迷路切除术组眩晕控制率为 100%(26/26),所有患者迷路切除后均丧失听力,听力损失率为 100%。两组眩晕控制率差异无统计学意义(P>0.05);TSCP 组听力损失率明显低于迷路切除术组(P<0.00)。TSCP 组从失衡中恢复的中位数时间为 15 天,迷路切除术组为 21 天,差异有统计学意义(P<0.05)。两组 FLS 差异无统计学意义(P>0.05)。

结论

与迷路切除术相比,TSCP 能以较高的概率保留听力;同时,耳石器官功能的保留使患者前庭代偿更快。

证据水平

3 级。喉镜,133:3178-3184,2023。

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