Li Xiaofei, Li Xiaoyi, Lyu Yafeng, Jian Huirong, Li Yawei, Wang Jing, Li Wenjuan, Wang Ruyan, Hu Yinghui, Fan Zhaomin, Wang Haibo, Zhang Daogong
Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital Shandong University Jinan Shandong China.
Shandong Provincial Vertigo, Dizziness Medical Center Jinan Shandong China.
Laryngoscope Investig Otolaryngol. 2024 Aug 21;9(4):e1313. doi: 10.1002/lio2.1313. eCollection 2024 Aug.
To retrospectively analyze clinical features in adolescent Menière's disease (MD).
The medical records of adolescents with MD (11-17 years old) from May 2014 to March 2023 in Shandong Provincial ENT Hospital were retrospectively analyzed, including clinical features, a battery of auditory and vestibular function tests, sensory organization test, and imaging assessments. Patients with recurrent vertigo of childhood (RVC) were as controls.
Compared with RVC, adolescent MD showed higher pure tone average threshold ( < .001), lower speech discrimination score ( = .014), and lower otoacoustic emission pass rates ( = .005). Adolescents with MD exhibited significant reduction in equilibrium score (Conditions 1, 5, and 6; 1 = .035; 5 = .033; 6 = .003), composite sensory score ( = .014), and vestibular sensory score ( = .029). Adolescents with bilateral MD exhibited worse performance in equilibrium score and strategy score compared to adolescents with unilateral MD. For the affected ear, the more severe endolymphatic hydrops detected by gadolinium-enhanced magnetic resonance imaging, the higher the auditory brainstem response threshold ( = .850, = .007), and the lower the otoacoustic emission pass rate ( = -.976, < .001).
Adolescent MD has similar vestibular information inputs with that of RVC, but the ability for the nerve center to use these clues to maintain balance is worse in adolescents with MD. There were potential differences in vestibular weights in adolescents with unilateral and bilateral MD, also potential effects on vision and proprioception.
Level 4.
回顾性分析青少年梅尼埃病（MD）的临床特征。
回顾性分析2014年5月至2023年3月在山东省耳鼻喉医院就诊的11至17岁青少年MD患者的病历，包括临床特征、一系列听力学和前庭功能测试、感觉组织测试及影像学评估。以儿童复发性眩晕（RVC）患者作为对照。
与RVC相比，青少年MD患者的纯音平均听阈更高（<0.001），言语识别得分更低（=0.014），耳声发射通过率更低（=0.005）。MD青少年患者的平衡得分（条件1、5和6；1=0.035；5=0.033；6=0.003）、综合感觉得分（=0.014）和前庭感觉得分（=0.029）显著降低。与单侧MD青少年相比，双侧MD青少年在平衡得分和策略得分方面表现更差。对于患耳，钆增强磁共振成像检测到的内淋巴积水越严重，听性脑干反应阈值越高（=0.850，=0.007），耳声发射通过率越低（=-0.976，<0.001）。
青少年MD与RVC的前庭信息输入相似，但MD青少年患者神经中枢利用这些线索维持平衡的能力较差。单侧和双侧MD青少年在前庭权重方面存在潜在差异，对视觉和本体感觉也可能有影响。
4级。
