National Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, China.
National Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, China.
Ecotoxicol Environ Saf. 2023 May;256:114882. doi: 10.1016/j.ecoenv.2023.114882. Epub 2023 Apr 8.
Cadmium (Cd) is a major environmental pollutant and poses a risk of transfer into the food chain through contaminated plants. Mechanisms underlying Cd tolerance and hyperaccumulation in plants are not fully understood. Proteomics-based approaches facilitate an in-depth understanding of plant responses to Cd stress at the systemic level by identifying Cd-inducible differentially abundant proteins (DAPs). In this review, we summarize studies related to proteomic changes associated with Cd-tolerance mechanisms in Cd-tolerant crops and Cd-hyperaccumulating plants, especially the similarities and differences across plant species. The enhanced DAPs identified through proteomic studies can be potential targets for developing Cd-hyperaccumulators to remediate Cd-contaminated environments and Cd-tolerant crops with low Cd content in the edible organs. This is of great significance for ensuring the food security of an exponentially growing global population. Finally, we discuss the methodological drawbacks in current proteomic studies and propose that better protocols and advanced techniques should be utilized to further strengthen the reliability and applicability of future Cd-stress-related studies in plants. This review provides insights into the improvement of phytoremediation efficiency and an in-depth study of the molecular mechanisms of Cd enrichment in plants.
镉 (Cd) 是一种主要的环境污染物，通过污染的植物有向食物链转移的风险。植物对镉的耐受和超积累的机制尚不完全清楚。基于蛋白质组学的方法通过鉴定镉诱导的差异丰度蛋白（DAPs），有助于深入了解植物对镉胁迫的系统水平响应。在这篇综述中，我们总结了与耐镉作物和镉超积累植物的镉耐受机制相关的蛋白质组变化研究，特别是跨物种的相似性和差异。通过蛋白质组学研究鉴定出的增强的 DAPs 可以成为开发镉超积累植物的潜在目标，以修复镉污染环境和镉含量低的可食用器官的镉耐受作物。这对于确保全球人口呈指数增长的食品安全具有重要意义。最后，我们讨论了当前蛋白质组学研究中的方法学缺陷，并提出应利用更好的方案和先进技术，进一步加强未来植物中与镉胁迫相关研究的可靠性和适用性。这篇综述为提高植物修复效率提供了深入了解，并深入研究了植物中镉富集的分子机制。
