IEEE J Biomed Health Inform. 2023 Jul;27(7):3234-3245. doi: 10.1109/JBHI.2023.3265805. Epub 2023 Jun 30.
Depression is a serious and common psychiatric disease characterized by emotional and cognitive dysfunction. In addition, the rates of clinical diagnosis and treatment for depression are low. Therefore, the accurate recognition of depression is important for its effective treatment. Electroencephalogram (EEG) signals, which can objectively reflect the inner states of human brains, are regarded as promising physiological tools that can enable effective and efficient clinical depression diagnosis and recognition. However, one of the challenges regarding EEG-based depression recognition involves sufficiently optimizing the spatial information derived from the multichannel space of EEG signals. Consequently, we propose an adaptive channel fusion method via improved focal loss (FL) functions for depression recognition based on EEG signals to effectively address this challenge. In this method, we propose two improved FL functions that can enhance the separability of hard examples by upweighting their losses as optimization objectives and can optimize the channel weights by a proposed adaptive channel fusion framework. The experimental results obtained on two EEG datasets show that the developed channel fusion method can achieve improved classification performance. The learned channel weights include the individual characteristics of each EEG epoch, which can effectively optimize the spatial information of each EEG epoch via the channel fusion method. In addition, the proposed method performs better than the state-of-the-art channel fusion methods.
抑郁症是一种严重且常见的精神疾病,其特征为情绪和认知功能障碍。此外,抑郁症的临床诊断和治疗率较低。因此,准确识别抑郁症对于其有效治疗非常重要。脑电图(EEG)信号可以客观地反映人脑的内部状态,被视为有前途的生理工具,可实现有效的临床抑郁症诊断和识别。然而,基于 EEG 的抑郁症识别面临的挑战之一是充分优化 EEG 信号多通道空间中提取的空间信息。因此,我们提出了一种基于 EEG 信号的自适应通道融合方法,通过改进的焦点损失(FL)函数进行抑郁症识别,以有效应对这一挑战。在该方法中,我们提出了两种改进的 FL 函数,它们可以通过加重优化目标的损失来提高硬例的可分性,并可以通过提出的自适应通道融合框架来优化通道权重。在两个 EEG 数据集上的实验结果表明,所提出的通道融合方法可以实现更好的分类性能。所学习的通道权重包括每个 EEG 时段的个体特征,通过通道融合方法可以有效地优化每个 EEG 时段的空间信息。此外,与最先进的通道融合方法相比,所提出的方法表现更好。